PMID- 26889144
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160218
LR  - 20240324
IS  - 1662-6664 (Print)
IS  - 1662-6672 (Electronic)
IS  - 1662-6664 (Linking)
VI  - 31
IP  - 6
DP  - 2015 Dec
TI  - How Effective Are Percutaneous Liver-Directed Therapies in Patients with 
      Non-Colorectal Liver Metastases?
PG  - 406-13
LID - 10.1159/000440677 [doi]
AB  - BACKGROUND: The purpose of this review is to demonstrate the clinical 
      indications, technical developments, and outcome of liver-directed therapies in 
      interventional oncology of non-colorectal liver metastases. METHODS: 
      Liver-directed therapies are classified into vascular transarterial techniques 
      such as chemoperfusion (TACP), chemoembolization (TACE), radioembolization 
      (selective internal radiation therapy (SIRT)), and chemosaturation, as well as 
      thermal ablation techniques like microwave ablation (MWA), radiofrequency 
      ablation (RFA), laser-induced thermotherapy (LITT), cryotherapy, and irreversible 
      electroporation (IRE). The authors searched the database PubMed using the 
      following terms: 'image-guided tumor ablation', 'thermal ablation therapies', 
      'liver metastases of uveal melanoma', 'neuroendocrine carcinoma', 'breast 
      cancer', and 'non-colorectal liver metastases'. RESULTS: Various combinations of 
      the above-mentioned therapy protocols are possible. In neuroendocrine carcinomas, 
      oligonodular liver metastases are treated successfully via thermal ablation like 
      RFA, LITT, or MWA, and diffuse involvement via TACE or SIRT. Although liver 
      involvement in breast cancer is a systemic disease, non-responding nodular 
      metastases can be controlled via RFA or LITT. In ocular or cutaneous melanoma, 
      thermal ablation is rarely considered as an interventional treatment option, as 
      opposed to TACE, SIRT, or chemosaturation. Rarely liver-directed therapies are 
      used in pancreatic cancer, most likely due to problems such as biliary digestive 
      communications after surgery and the risk of infections. Rare indications for 
      thermal ablation are liver metastases of other primary cancers like non-small 
      cell lung, gastric, and ovarian cancer. CONCLUSION: Interventional oncological 
      techniques play a role in patients with liver-dominant metastases.
FAU - Vogl, Thomas J
AU  - Vogl TJ
AD  - Institute for Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
FAU - Emam, Ahmed
AU  - Emam A
AD  - Institute for Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
FAU - Naguib, Nagy N
AU  - Naguib NN
AD  - Institute for Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main, Germany; 
      Department of Diagnostic and Interventional Radiology, University of Alexandria, 
      Alexandria, Egypt.
FAU - Eichler, Katrin
AU  - Eichler K
AD  - Institute for Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
FAU - Zangos, Stefan
AU  - Zangos S
AD  - Institute for Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20151201
PL  - Switzerland
TA  - Viszeralmedizin
JT  - Viszeralmedizin
JID - 101498857
PMC - PMC4748795
OTO - NOTNLM
OT  - Laser ablation
OT  - Microwave ablation
OT  - Non-colorectal liver metastases
OT  - Radiofrequency ablation
EDAT- 2016/02/19 06:00
MHDA- 2016/02/19 06:01
PMCR- 2016/12/01
CRDT- 2016/02/19 06:00
PHST- 2016/02/19 06:00 [entrez]
PHST- 2016/02/19 06:00 [pubmed]
PHST- 2016/02/19 06:01 [medline]
PHST- 2016/12/01 00:00 [pmc-release]
AID - vim-0031-0406 [pii]
AID - 10.1159/000440677 [doi]
PST - ppublish
SO  - Viszeralmedizin. 2015 Dec;31(6):406-13. doi: 10.1159/000440677. Epub 2015 Dec 1.