PMID- 26889799 OWN - NLM STAT- MEDLINE DCOM- 20161019 LR - 20181202 IS - 1878-6448 (Electronic) IS - 1053-8135 (Linking) VI - 38 IP - 1 DP - 2016 TI - Can Cognitive Behavioral Therapy for Insomnia also treat fatigue, pain, and mood symptoms in individuals with traumatic brain injury? - A multiple case report. PG - 59-69 LID - 10.3233/NRE-151296 [doi] AB - BACKGROUND: Individuals with traumatic brain injury (TBI) often develop sleep disorders post-injury. The most common one is insomnia, which can exacerbate other post-injury symptoms, including fatigue, impaired cognition, depression, anxiety, and pain. Cognitive Behavioral Therapy for Insomnia (CBT-I) is a manualized treatment that effectively treats insomnia with secondary effects on cognition, mood, and pain in various populations. OBJECTIVE: This paper reviews the use of CBT-I for three participants with TBI of different severities. METHODS: Pre- and post-treatment assessments of insomnia, fatigue, depression, anxiety, and pain were conducted. Mood was further assessed at follow-up. Minimal clinically important difference (MCID) scores derived from the research literature were used to establish clinically meaningful symptom improvement on self-report questionnaires. RESULTS: The reduction in insomnia severity scores for all three participants were not large enough to be considered a clinically significant improvement following CBT-I, although trends toward improvement were observed. However, all participants showed clinically significant reductions in anxiety at post-treatment; the effects persisted for 2 participants at follow-up. Reductions in depression symptoms were observed for 2 participants at post-treatment, and treatment effects persisted for 1 participant at follow-up. One participant endorsed clinically significant improvements in fatigue and pain severity. CONCLUSIONS: We conclude that CBT-I may provide secondary benefits for symptoms commonly experienced by individuals with TBI, especially mood disturbances. FAU - Lu, William AU - Lu W AD - Rusk Rehabilitation, New York University Langone Medical Center, New York, NY, USA. FAU - Krellman, Jason W AU - Krellman JW AD - Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. FAU - Dijkers, Marcel P AU - Dijkers MP AD - Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. LA - eng GR - 5U49CE002092-02/CE/NCIPC CDC HHS/United States PT - Case Reports PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - Netherlands TA - NeuroRehabilitation JT - NeuroRehabilitation JID - 9113791 SB - IM MH - Adult MH - Affect MH - Anxiety/diagnosis/etiology/*therapy MH - Brain Injuries/complications/diagnosis/*therapy MH - Cognitive Behavioral Therapy/*methods MH - Depression/diagnosis/etiology/*therapy MH - Fatigue/diagnosis/etiology/*therapy MH - Female MH - Humans MH - Male MH - Middle Aged MH - Pain/diagnosis/etiology MH - Pain Management/*methods MH - Self Report MH - Sleep Initiation and Maintenance Disorders/diagnosis/etiology/*therapy OTO - NOTNLM OT - Insomnia OT - case study OT - cognitive behavioral therapy OT - traumatic brain injury EDAT- 2016/02/20 06:00 MHDA- 2016/11/11 06:00 CRDT- 2016/02/19 06:00 PHST- 2016/02/19 06:00 [entrez] PHST- 2016/02/20 06:00 [pubmed] PHST- 2016/11/11 06:00 [medline] AID - NRE1296 [pii] AID - 10.3233/NRE-151296 [doi] PST - ppublish SO - NeuroRehabilitation. 2016;38(1):59-69. doi: 10.3233/NRE-151296.