PMID- 26890962
OWN - NLM
STAT- MEDLINE
DCOM- 20170316
LR  - 20211203
IS  - 1740-0929 (Electronic)
IS  - 1344-3941 (Linking)
VI  - 87
IP  - 8
DP  - 2016 Aug
TI  - Kid depletion in mouse oocytes associated with multinucleated blastomere 
      formation and inferior embryo development.
PG  - 1048-54
LID - 10.1111/asj.12530 [doi]
AB  - This study investigated the knockdown (KD) of Kid on maturation developmental 
      competence and multinucleation of mouse germinal vesicle (GV) oocytes after 
      parthenogenetic activation. Data revealed that Kid messenger RNA (mRNA) was 
      expressed in GV and MII stage oocyte and 1- and 2-cell embryos. Additionally, Kid 
      mRNA expression in the Kid KD group decreased by nearly 46% compared to the 
      control small interfering RNA (siRNA) groups. The rate of multinucleated embryos 
      in the Kid KD group (52.4%) was significantly higher (P < 0.05) than the control 
      siRNA group (4.7%). Finally, the developmental rates were significantly lower in 
      the Kid siRNA group at > 4-cell stage (28.6% vs. 53.5%) and the blastocyst stage 
      (2.4% vs. 23.3%) compared to the control siRNA groups. Suppression of Kid using 
      siRNA caused multinucleation in early embryos with high frequency and it may 
      increase 2- to 4-cell arrested embryos and reduce the developmental competence to 
      blastocyst.
CI  - (c) 2016 Japanese Society of Animal Science.
FAU - Egashira, Akiyoshi
AU  - Egashira A
AD  - Kuramoto Women's Clinic, Fukuoka, Japan.
FAU - Yamauchi, Nobuhiko
AU  - Yamauchi N
AD  - Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu 
      University, Fukuoka, Japan.
FAU - Islam, Md Rashedul
AU  - Islam MR
AD  - Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu 
      University, Fukuoka, Japan.
AD  - Department of Genetics and Animal Breeding, Hajee Mohammad Danesh Science and 
      Technology University, Dinajpur, Bangladesh.
FAU - Yamagami, Kazuki
AU  - Yamagami K
AD  - Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu 
      University, Fukuoka, Japan.
FAU - Tanaka, Asami
AU  - Tanaka A
AD  - Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu 
      University, Fukuoka, Japan.
FAU - Suyama, Hikaru
AU  - Suyama H
AD  - Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu 
      University, Fukuoka, Japan.
FAU - El-Sayed, El-Sharawy Mohamed
AU  - El-Sayed el-SM
AD  - Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu 
      University, Fukuoka, Japan.
AD  - Animal Production Department, Kafrelsheikh University, Kafrelsheikh, Egypt.
FAU - Tabata, Shoji
AU  - Tabata S
AD  - Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu 
      University, Fukuoka, Japan.
FAU - Kuramoto, Takashi
AU  - Kuramoto T
AD  - Kuramoto Women's Clinic, Fukuoka, Japan.
LA  - eng
PT  - Journal Article
DEP - 20160218
PL  - Australia
TA  - Anim Sci J
JT  - Animal science journal = Nihon chikusan Gakkaiho
JID - 100956805
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (RNA, Messenger)
RN  - 0 (RNA, Small Interfering)
RN  - EC 3.6.1.- (Kid protein, mouse)
RN  - EC 3.6.4.4 (Kinesins)
SB  - IM
MH  - Animals
MH  - *Blastomeres
MH  - Cells, Cultured
MH  - DNA-Binding Proteins/*genetics
MH  - Embryonic Development/*genetics
MH  - Female
MH  - Gene Expression
MH  - *Gene Knockdown Techniques
MH  - *Giant Cells
MH  - Kinesins/*genetics
MH  - Mice
MH  - Mice, Inbred ICR
MH  - Oocytes/*growth & development
MH  - Parthenogenesis
MH  - RNA, Messenger
MH  - RNA, Small Interfering
OTO - NOTNLM
OT  - Kid
OT  - multinucleated blastomere
OT  - parthenogenetic embryos
OT  - siRNA
EDAT- 2016/02/19 06:00
MHDA- 2017/03/17 06:00
CRDT- 2016/02/19 06:00
PHST- 2015/05/13 00:00 [received]
PHST- 2015/07/13 00:00 [revised]
PHST- 2015/07/23 00:00 [accepted]
PHST- 2016/02/19 06:00 [entrez]
PHST- 2016/02/19 06:00 [pubmed]
PHST- 2017/03/17 06:00 [medline]
AID - 10.1111/asj.12530 [doi]
PST - ppublish
SO  - Anim Sci J. 2016 Aug;87(8):1048-54. doi: 10.1111/asj.12530. Epub 2016 Feb 18.