PMID- 26892480 OWN - NLM STAT- MEDLINE DCOM- 20170522 LR - 20170522 IS - 1346-8138 (Electronic) IS - 0385-2407 (Linking) VI - 43 IP - 8 DP - 2016 Aug TI - Three cases of pigmented cosmetic dermatitis-like eruptions associated with primary Sjogren's syndrome or anti-SSA antibody. PG - 947-50 LID - 10.1111/1346-8138.13300 [doi] AB - Pigmented cosmetic dermatitis-like (Riehl's melanosis-like) pigmentation was reported in three of 27 patients with primary Sjogren's syndrome. But case reports of such eruptions are rare. We describe three cases of such eruptions associated with primary Sjogren's syndrome or anti-SSA antibody and possible associations with specific types of human leukocyte antigen (HLA) and infiltrating lymphocytes. These middle-aged Japanese women had reticular facial pigmentation and histopathological examination revealed interface dermatitis, melanophages, and dense lymphocytic infiltration around hair follicles and sweat ducts. HLA typing revealed common antigenic equivalents or genetic typing of HLA-A2, DR52, DPA1(02:02) and DPB1(05:01). Immunohistochemical staining revealed major subsets of T cells to be CD8 and CD45RO. Some Foxp3- and few IL17-positive cells were found in strong contrast to the major CD4 subset of infiltrated T cells in annular erythema associated with Sjogren's syndrome. Apparently, our patients' pigmentation represented a specific etiology associated with primary Sjogren's syndrome or anti-SSA antibody. CI - (c) 2016 Japanese Dermatological Association. FAU - Takeo, Naoko AU - Takeo N AD - Department of Dermatology, Oita University, Kyoto, Japan. FAU - Sakai, Takashi AU - Sakai T AD - Department of Dermatology, Oita University, Kyoto, Japan. FAU - Saito-Shono, Tomoko AU - Saito-Shono T AD - Department of Dermatology, Oita University, Kyoto, Japan. FAU - Ishikawa, Kazushi AU - Ishikawa K AD - Department of Dermatology, Oita University, Kyoto, Japan. FAU - Hatano, Yutaka AU - Hatano Y AD - Department of Dermatology, Oita University, Kyoto, Japan. FAU - Katagiri, Kazumoto AU - Katagiri K AD - Department of Dermatology, Oita University, Kyoto, Japan. FAU - Takahashi, Yoshihiro AU - Takahashi Y AD - Department of Oral and Maxillo-Facial Surgery, Oita University, Kyoto, Japan. FAU - Kawano, Kenji AU - Kawano K AD - Department of Oral and Maxillo-Facial Surgery, Oita University, Kyoto, Japan. FAU - Kimoto, Kenichi AU - Kimoto K AD - Department of Ophthalmology, Oita University, Kyoto, Japan. FAU - Kubota, Toshiaki AU - Kubota T AD - Department of Ophthalmology, Oita University, Kyoto, Japan. FAU - Eshima, Nobuoki AU - Eshima N AD - Department of Biostatistics, Faculty of Medicine, Oita University, Kyoto, Japan. FAU - Kojima, Hiroto AU - Kojima H AD - HLA Foundation Laboratory, Kyoto, Japan. FAU - Fujiwara, Sakuhei AU - Fujiwara S AD - Department of Dermatology, Oita University, Kyoto, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20160219 PL - England TA - J Dermatol JT - The Journal of dermatology JID - 7600545 RN - 0 (Antibodies, Antinuclear) RN - 0 (SS-A antibodies) SB - IM MH - Aged MH - Antibodies, Antinuclear/*blood MH - Dermatitis/etiology/*immunology/*pathology MH - Female MH - Histocompatibility Testing MH - Humans MH - Middle Aged MH - Pigmentation Disorders/etiology/immunology/pathology MH - Sjogren's Syndrome/complications/immunology/*pathology OTO - NOTNLM OT - Riehl's melanosis OT - anti-SSA antibody OT - human leukocyte antigen typing OT - pigmented cosmetic dermatitis-like eruption OT - primary Sjogren's syndrome EDAT- 2016/02/20 06:00 MHDA- 2017/05/23 06:00 CRDT- 2016/02/20 06:00 PHST- 2015/11/07 00:00 [received] PHST- 2015/12/15 00:00 [accepted] PHST- 2016/02/20 06:00 [entrez] PHST- 2016/02/20 06:00 [pubmed] PHST- 2017/05/23 06:00 [medline] AID - 10.1111/1346-8138.13300 [doi] PST - ppublish SO - J Dermatol. 2016 Aug;43(8):947-50. doi: 10.1111/1346-8138.13300. Epub 2016 Feb 19.