PMID- 26897388 OWN - NLM STAT- MEDLINE DCOM- 20160902 LR - 20220410 IS - 1097-6787 (Electronic) IS - 0190-9622 (Print) IS - 0190-9622 (Linking) VI - 74 IP - 5 DP - 2016 May TI - Using the American College of Rheumatology (ACR) and Systemic Lupus International Collaborating Clinics (SLICC) criteria to determine the diagnosis of systemic lupus erythematosus (SLE) in patients with subacute cutaneous lupus erythematosus (SCLE). PG - 862-9 LID - S0190-9622(15)02605-5 [pii] LID - 10.1016/j.jaad.2015.12.029 [doi] AB - BACKGROUND: Approximately 50% of patients with subacute cutaneous lupus erythematosus (SCLE) meet criteria for systemic lupus erythematosus (SLE). The Systemic Lupus International Collaborating Clinics (SLICC) developed new SLE criteria to improve the American College of Rheumatology (ACR) criteria but the SLICC criteria have not been evaluated in patients with SCLE. OBJECTIVE: We sought to determine how patients with SCLE/SLE meet the ACR and SLICC criteria to compare the 2 sets of criteria. METHODS: This was a retrospective analysis of 107 patients with SCLE enrolled in a database at the University of Pennsylvania. RESULTS: Patients with SCLE/SLE were more likely than those with only SCLE to have oral ulcers, positive anti-double-stranded DNA antibodies, and positive antinuclear antibody test findings using both sets of criteria. Patients with SCLE/SLE were also more likely to have low complement using the SLICC criteria. There was a statistically insignificant increase in individuals meeting the SLICC criteria. LIMITATIONS: Not all patients received comprehensive laboratory testing. CONCLUSIONS: Most patients with SCLE who formally meet criteria for SLE do so based on the laboratory and mucocutaneous criteria. Neither the ACR nor SLICC criteria distinguish patients with SCLE and major internal disease from patients with SCLE without major internal disease. CI - Published by Elsevier Inc. FAU - Tiao, Janice AU - Tiao J AD - Corporal Michael J. Crescenz Philadelphia Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Feng, Rui AU - Feng R AD - Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Carr, Kasey AU - Carr K AD - Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Okawa, Joyce AU - Okawa J AD - Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Werth, Victoria P AU - Werth VP AD - Corporal Michael J. Crescenz Philadelphia Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: werth@mail.med.upenn.edu. LA - eng GR - I01 BX000706/BX/BLRD VA/United States GR - K24 AR002207/AR/NIAMS NIH HHS/United States GR - K24-AR 02207/AR/NIAMS NIH HHS/United States PT - Comparative Study PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, U.S. Gov't, Non-P.H.S. DEP - 20160218 PL - United States TA - J Am Acad Dermatol JT - Journal of the American Academy of Dermatology JID - 7907132 RN - 0 (Antibodies, Antinuclear) SB - IM MH - Adult MH - Aged MH - Antibodies, Antinuclear/*immunology MH - Cohort Studies MH - Cooperative Behavior MH - Databases, Factual MH - Diagnosis, Differential MH - Female MH - Humans MH - Lupus Erythematosus, Cutaneous/*classification/diagnosis/immunology MH - Lupus Erythematosus, Systemic/*classification/diagnosis/immunology MH - Male MH - Middle Aged MH - Practice Guidelines as Topic/*standards MH - Retrospective Studies MH - Rheumatology/standards MH - Risk Assessment MH - Societies, Medical/standards PMC - PMC4879000 MID - NIHMS746372 OTO - NOTNLM OT - American College of Rheumatology OT - Systemic Lupus International Collaborating Clinics OT - classification criteria OT - cutaneous lupus erythematosus OT - subacute cutaneous lupus erythematosus OT - systemic lupus erythematosus COIS- Conflict of Interest Disclosure: None Declared EDAT- 2016/02/22 06:00 MHDA- 2016/09/03 06:00 PMCR- 2017/05/01 CRDT- 2016/02/22 06:00 PHST- 2015/07/14 00:00 [received] PHST- 2015/12/01 00:00 [revised] PHST- 2015/12/10 00:00 [accepted] PHST- 2016/02/22 06:00 [entrez] PHST- 2016/02/22 06:00 [pubmed] PHST- 2016/09/03 06:00 [medline] PHST- 2017/05/01 00:00 [pmc-release] AID - S0190-9622(15)02605-5 [pii] AID - 10.1016/j.jaad.2015.12.029 [doi] PST - ppublish SO - J Am Acad Dermatol. 2016 May;74(5):862-9. doi: 10.1016/j.jaad.2015.12.029. Epub 2016 Feb 18.