PMID- 26906710
OWN - NLM
STAT- MEDLINE
DCOM- 20160712
LR  - 20181202
IS  - 0412-4081 (Print)
IS  - 0412-4081 (Linking)
VI  - 52
IP  - 2
DP  - 2016 Feb
TI  - [Ocular immune reconstitution inflammatory syndrome].
PG  - 150-3
LID - 10.3760/cma.j.issn.0412-4081.2016.02.017 [doi]
AB  - Immune reconstitution inflammatory syndrome (IRIS) is a collection of 
      inflammatory disorders associated with paradoxical worsening of preexisting 
      infectious processes or emerging diseases or even dead after the initiation of 
      highly active antiretroviral therapy (HAART) in human immunodeficiency virus 
      (HIV) infected individuals in a period of recovery of immune function. Ocular 
      immune reconstitution inflammatory syndrome is mainly caused by cytomegalovirus 
      which performing a series of ocular inflammation accompanied with the increase of 
      CD4+ T lymphocytes, such as cytomegalovirus retinitis, after HAART. With HAART 
      widely used, the patients of IRIS gradually increased. But the clinical 
      presentations of IRIS were various because of different pathogens. This review 
      summarized the clinical manifestations, risk factors, diagnosis and treatment of 
      ocular IRIS.
FAU - Ma, N
AU  - Ma N
AD  - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese 
      Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, 
      China.
FAU - Ye, J J
AU  - Ye JJ
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Zhonghua Yan Ke Za Zhi
JT  - [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
JID - 16210540R
SB  - IM
MH  - Antiretroviral Therapy, Highly Active/*adverse effects
MH  - CD4-Positive T-Lymphocytes
MH  - Cytomegalovirus Retinitis/etiology
MH  - HIV Infections
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/drug therapy/*etiology/immunology
MH  - Risk Factors
EDAT- 2016/02/26 06:00
MHDA- 2016/07/13 06:00
CRDT- 2016/02/25 06:00
PHST- 2016/02/25 06:00 [entrez]
PHST- 2016/02/26 06:00 [pubmed]
PHST- 2016/07/13 06:00 [medline]
AID - 10.3760/cma.j.issn.0412-4081.2016.02.017 [doi]
PST - ppublish
SO  - Zhonghua Yan Ke Za Zhi. 2016 Feb;52(2):150-3. doi: 
      10.3760/cma.j.issn.0412-4081.2016.02.017.