PMID- 26906720
OWN - NLM
STAT- MEDLINE
DCOM- 20161230
LR  - 20240216
IS  - 1878-1705 (Electronic)
IS  - 1567-5769 (Print)
IS  - 1567-5769 (Linking)
VI  - 34
DP  - 2016 May
TI  - Tissue-resident dendritic cells and diseases involving dendritic cell 
      malfunction.
PG  - 1-15
LID - S1567-5769(16)30042-X [pii]
LID - 10.1016/j.intimp.2016.02.007 [doi]
AB  - Dendritic cells (DCs) control immune responses and are central to the development 
      of immune memory and tolerance. DCs initiate and orchestrate immune responses in 
      a manner that depends on signals they receive from microbes and cellular 
      environment. Although DCs consist mainly of bone marrow-derived and resident 
      populations, a third tissue-derived population resides the spleen and lymph nodes 
      (LNs), different subsets of tissue-derived DCs have been identified in the blood, 
      spleen, lymph nodes, skin, lung, liver, gut and kidney to maintain the tolerance 
      and control immune responses. Tissue-resident DCs express different receptors for 
      microbe-associated molecular patterns (MAMPs) and damage-associated molecular 
      patterns (DAMPs), which were activated to promote the production of pro- or 
      anti-inflammatory cytokines. Malfunction of DCs contributes to diseases such as 
      autoimmunity, allergy, and cancer. It is therefore important to update the 
      knowledge about resident DC subsets and diseases associated with DC malfunction.
CI  - Published by Elsevier B.V.
FAU - Chen, Keqiang
AU  - Chen K
AD  - Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 
      200072, China; Cancer and Inflammation Program, Center for Cancer Research, 
      National Cancer Institute at Frederick, Frederick, MD 21702, USA; Laboratory of 
      Inflammation Biology, Department of Biological Sciences, Virginia Polytechnic 
      Institute and State University, Blacksburg, VA 24061-0910, USA. Electronic 
      address: keqiangc8@gmail.com.
FAU - Wang, Ji Ming
AU  - Wang JM
AD  - Cancer and Inflammation Program, Center for Cancer Research, National Cancer 
      Institute at Frederick, Frederick, MD 21702, USA. Electronic address: 
      wangji@mail.nih.gov.
FAU - Yuan, Ruoxi
AU  - Yuan R
AD  - Laboratory of Inflammation Biology, Department of Biological Sciences, Virginia 
      Polytechnic Institute and State University, Blacksburg, VA 24061-0910, USA.
FAU - Yi, Xiang
AU  - Yi X
AD  - Cancer and Inflammation Program, Center for Cancer Research, National Cancer 
      Institute at Frederick, Frederick, MD 21702, USA.
FAU - Li, Liangzhu
AU  - Li L
AD  - Cancer and Inflammation Program, Center for Cancer Research, National Cancer 
      Institute at Frederick, Frederick, MD 21702, USA.
FAU - Gong, Wanghua
AU  - Gong W
AD  - Cancer and Inflammation Program, Center for Cancer Research, National Cancer 
      Institute at Frederick, Frederick, MD 21702, USA; Basic Research Program, Leidos 
      Biomedical Research, Inc., Frederick, MD 21702, USA.
FAU - Yang, Tianshu
AU  - Yang T
AD  - Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 
      200072, China.
FAU - Li, Liwu
AU  - Li L
AD  - Laboratory of Inflammation Biology, Department of Biological Sciences, Virginia 
      Polytechnic Institute and State University, Blacksburg, VA 24061-0910, USA.
FAU - Su, Shaobo
AU  - Su S
AD  - Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 
      200072, China.
LA  - eng
GR  - HHSN261200800001C/RC/CCR NIH HHS/United States
GR  - HHSN261200800001E/CA/NCI NIH HHS/United States
GR  - Z01 BC010015-13/ImNIH/Intramural NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, N.I.H., Intramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20160222
PL  - Netherlands
TA  - Int Immunopharmacol
JT  - International immunopharmacology
JID - 100965259
RN  - 0 (Cytokines)
RN  - 0 (Inflammation Mediators)
RN  - 0 (Receptors, Pattern Recognition)
SB  - IM
MH  - Animals
MH  - Autoimmune Diseases/*immunology/therapy
MH  - Cytokines/metabolism
MH  - Dendritic Cells/*immunology/transplantation
MH  - Humans
MH  - Hypersensitivity/*immunology/therapy
MH  - Immune Tolerance
MH  - Immunologic Memory
MH  - Immunotherapy/*methods
MH  - Inflammation Mediators/metabolism
MH  - Neoplasms/*immunology/therapy
MH  - Receptors, Pattern Recognition/metabolism
PMC - PMC4818737
MID - NIHMS762152
OTO - NOTNLM
OT  - Autoimmunity
OT  - Cancer
OT  - DC-related diseases
OT  - Dendritic cells
OT  - Resident DCs
EDAT- 2016/02/26 06:00
MHDA- 2016/12/31 06:00
PMCR- 2017/05/01
CRDT- 2016/02/25 06:00
PHST- 2015/11/25 00:00 [received]
PHST- 2016/02/05 00:00 [accepted]
PHST- 2016/02/25 06:00 [entrez]
PHST- 2016/02/26 06:00 [pubmed]
PHST- 2016/12/31 06:00 [medline]
PHST- 2017/05/01 00:00 [pmc-release]
AID - S1567-5769(16)30042-X [pii]
AID - 10.1016/j.intimp.2016.02.007 [doi]
PST - ppublish
SO  - Int Immunopharmacol. 2016 May;34:1-15. doi: 10.1016/j.intimp.2016.02.007. Epub 
      2016 Feb 22.