PMID- 26915299
OWN - NLM
STAT- MEDLINE
DCOM- 20171019
LR  - 20181202
IS  - 1099-0496 (Electronic)
IS  - 1099-0496 (Linking)
VI  - 51
IP  - 10
DP  - 2016 Oct
TI  - Influence of intrapulmonary percussive ventilation in upright position on 
      gastro-oesophageal reflux in infants.
PG  - 1065-1071
LID - 10.1002/ppul.23400 [doi]
AB  - OBJECTIVES: To determine the influence of physiotherapy using intrapulmonary 
      percussive ventilation on gastro-oesophageal reflux (GOR) in infants <1 year. 
      METHODS: In this controlled trial with intra-subject design, children were 
      studied using multichannel intraluminal impedance pH (pH-MII) monitoring over 
      24 hr, during which they received one 20-min session of intrapulmonary percussive 
      ventilation in upright position (IPV(R) ), 2 hr after their latest feeding. Two 
      hours after each feeding, the number of reflux episodes (RE) over a 20-min period 
      was registered for each infant and a mean per 20 min was calculated in order to 
      obtain a baseline value. The number of RE during IPV(R) intervention was compared 
      to baseline. RESULTS: Fifty infants with a median age of 133 days were recruited 
      of whom 21 were diagnosed with pathological GOR. During IPV(R) , the incidence of 
      RE in the entire group was significantly lower compared to baseline; median 
      (inter-quartile range [IQR]) 0 (0-1) versus 0.71 (0-1.33) RE, respectively, 
      P = 0.003. The subgroup with abnormal GOR showed also a significant decrease of 
      RE during IPV(R) ; median (IQR) 0 (0-1) versus 1.17 (0.55-2.16) RE, respectively, 
      P = 0.03. No difference was detected in the group with normal reflux; median 
      (IQR) 0.6 (0-1) compared to 0 (0-1) RE, respectively, P = 0.34. CONCLUSION: 
      IPV(R) does not induce, nor aggravate GOR in infants without and with 
      pathological GOR, respectively, but on the contrary decreases the number of RE in 
      patients with pathological reflux. Pediatr Pulmonol. 2016;51:1065-1071. (c) 2016 
      Wiley Periodicals, Inc.
CI  - (c) 2016 Wiley Periodicals, Inc.
FAU - Van Ginderdeuren, F
AU  - Van Ginderdeuren F
AD  - Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, 
      Brussels, Belgium. filip.vanginderdeuren@telenet.be.
AD  - Department of Physiotherapy, UZ Brussel, Brussels, Belgium. 
      filip.vanginderdeuren@telenet.be.
FAU - Kerckhofs, E
AU  - Kerckhofs E
AD  - Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, 
      Brussels, Belgium.
FAU - Deneyer, M
AU  - Deneyer M
AD  - Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, Brussels, 
      Belgium.
FAU - Vanlaethem, S
AU  - Vanlaethem S
AD  - Department of Physiotherapy, UZ Brussel, Brussels, Belgium.
FAU - Buyl, R
AU  - Buyl R
AD  - Department of Public Health, Biostatistics and Medical Informatics, Information 
      Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
FAU - Vandenplas, Y
AU  - Vandenplas Y
AD  - Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, Brussels, 
      Belgium.
LA  - eng
PT  - Journal Article
DEP - 20160224
PL  - United States
TA  - Pediatr Pulmonol
JT  - Pediatric pulmonology
JID - 8510590
SB  - IM
MH  - Electric Impedance
MH  - Female
MH  - Gastroesophageal Reflux/*therapy
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Infant
MH  - Male
MH  - Patient Positioning
MH  - *Physical Therapy Modalities
MH  - Treatment Outcome
OTO - NOTNLM
OT  - airway clearance techniques
OT  - children
OT  - physical therapy
OT  - respiratory physiotherapy
EDAT- 2016/02/27 06:00
MHDA- 2017/10/20 06:00
CRDT- 2016/02/27 06:00
PHST- 2015/10/05 00:00 [received]
PHST- 2015/12/07 00:00 [revised]
PHST- 2016/01/31 00:00 [accepted]
PHST- 2016/02/27 06:00 [pubmed]
PHST- 2017/10/20 06:00 [medline]
PHST- 2016/02/27 06:00 [entrez]
AID - 10.1002/ppul.23400 [doi]
PST - ppublish
SO  - Pediatr Pulmonol. 2016 Oct;51(10):1065-1071. doi: 10.1002/ppul.23400. Epub 2016 
      Feb 24.