PMID- 26920285 OWN - NLM STAT- MEDLINE DCOM- 20161028 LR - 20181202 IS - 1873-7072 (Electronic) IS - 0308-8146 (Linking) VI - 202 DP - 2016 Jul 1 TI - Dissipation, transfer and safety evaluation of emamectin benzoate in tea. PG - 199-204 LID - S0308-8146(15)30214-4 [pii] LID - 10.1016/j.foodchem.2015.11.069 [doi] AB - The dissipation and residue of emamectin benzoate in tea leaves and the residue transfer from tea leaves to tea brew were investigated by modified QuEChERS (quick, easy, cheap, effective, rugged and safe) combined with ultra performance liquid chromatography tandem mass (UPLC-MS/MS). The average recoveries ranged 85.3-101.3% with relative standard deviation (RSD) less than 15%. The limits of quantification (LOQ) were 0.005mgkg(-1) in tea leaves and 0.0004mgL(-1) in brew. Emamectin benzoate dissipated rapidly in tea with half-life (t1/2) of 1.0-1.3days. The terminal residues of emamectin benzoate were less than 0.062mgkg(-1). The leaching rate of emamectin benzoate from freshly-made tea to brew was <5%. The risk of emamectin benzoate at the recommended dosage was negligible to humans depending on risk quotient (RQ) value, that was lower than 1 significantly. This study could provide guidance for the safe use of emamectin benzoate and serve as a reference for the establishment of maximum residue limits (MRLs) in China. CI - Copyright (c) 2016. Published by Elsevier Ltd. FAU - Zhou, Li AU - Zhou L AD - Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Biology and Resources Utilization, Ministry of Agricultural, Hangzhou 310008, China. FAU - Luo, Fengjian AU - Luo F AD - Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Biology and Resources Utilization, Ministry of Agricultural, Hangzhou 310008, China. FAU - Zhang, Xinzhong AU - Zhang X AD - Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Biology and Resources Utilization, Ministry of Agricultural, Hangzhou 310008, China. FAU - Jiang, Yaping AU - Jiang Y AD - Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Biology and Resources Utilization, Ministry of Agricultural, Hangzhou 310008, China. FAU - Lou, Zhengyun AU - Lou Z AD - Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Biology and Resources Utilization, Ministry of Agricultural, Hangzhou 310008, China. FAU - Chen, Zongmao AU - Chen Z AD - Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Biology and Resources Utilization, Ministry of Agricultural, Hangzhou 310008, China. Electronic address: zmchen2006@163.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20151114 PL - England TA - Food Chem JT - Food chemistry JID - 7702639 RN - 0 (Tea) RN - 70288-86-7 (Ivermectin) RN - HVM3G4A01W (emamectin benzoate) SB - IM MH - Camellia sinensis/*chemistry MH - China MH - Chromatography, Liquid MH - *Food Contamination MH - Half-Life MH - Ivermectin/*analogs & derivatives/analysis MH - Plant Leaves/*chemistry MH - Tandem Mass Spectrometry MH - Tea/*chemistry/standards OTO - NOTNLM OT - Dissipation OT - Emamectin benzoate OT - Tea OT - Transfer OT - Ultra performance liquid chromatography-tandem mass spectrometry EDAT- 2016/02/28 06:00 MHDA- 2016/11/01 06:00 CRDT- 2016/02/28 06:00 PHST- 2014/07/13 00:00 [received] PHST- 2015/09/04 00:00 [revised] PHST- 2015/11/13 00:00 [accepted] PHST- 2016/02/28 06:00 [entrez] PHST- 2016/02/28 06:00 [pubmed] PHST- 2016/11/01 06:00 [medline] AID - S0308-8146(15)30214-4 [pii] AID - 10.1016/j.foodchem.2015.11.069 [doi] PST - ppublish SO - Food Chem. 2016 Jul 1;202:199-204. doi: 10.1016/j.foodchem.2015.11.069. Epub 2015 Nov 14.