PMID- 26923426
OWN - NLM
STAT- MEDLINE
DCOM- 20170614
LR  - 20170614
IS  - 1600-0838 (Electronic)
IS  - 0905-7188 (Linking)
VI  - 27
IP  - 2
DP  - 2017 Feb
TI  - Influence of treadmill training on bone structure under osteometabolic alteration 
      in rats subjected to high-fat diet.
PG  - 167-176
LID - 10.1111/sms.12650 [doi]
AB  - Nutrition and physical training have important roles in the accumulation and 
      maintenance of bone mass. The aim of this study was to evaluate, in 
      ovariectomized rats (OVX), the effects of treadmill training (T) with high-fat 
      diet (F) on weight gain and bone tissue properties with eight groups (n = 10) for 
      12 weeks: OVX SC (OVX, sedentary lifestyle, diet control); OVX SF; OVX TC; OVX 
      TF; SH SC (SHAM, sedentary lifestyle, diet control); SH SF; SH TC; and SH TF. 
      Weekly weight gain and final body composition were assessed. After euthanasia, 
      tibiae were analyzed. The trained animals had higher body weight (P = 0.001), 
      bone mineral density (P < 0.001), and trabecular bone (P < 0.001). The animals 
      with a high-fat diet showed higher global fat (P < 0.001), percentage of global 
      fat (P < 0.001) and deformation at impact (P = 0.031) and reduced tibial bone 
      mineral content (P = 0.036). Physical training improves bone microarchitecture, 
      without presenting an increase in impact resistance, and a high-fat diet 
      increases body fat and impairs bone mineralization.
CI  - (c) 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Macedo, A P
AU  - Macedo AP
AD  - Bioengineering Laboratory, Department of Biomechanics, Medicine and 
      Rehabilitation of the Locomotor System, Ribeirao Preto Medical School, University 
      of Sao Paulo, Sao Paulo, Brazil.
FAU - Shimano, R C
AU  - Shimano RC
AD  - Bioengineering Laboratory, Department of Biomechanics, Medicine and 
      Rehabilitation of the Locomotor System, Ribeirao Preto Medical School, University 
      of Sao Paulo, Sao Paulo, Brazil.
FAU - Ferrari, D T
AU  - Ferrari DT
AD  - Bioengineering Laboratory, Department of Biomechanics, Medicine and 
      Rehabilitation of the Locomotor System, Ribeirao Preto Medical School, University 
      of Sao Paulo, Sao Paulo, Brazil.
FAU - Issa, J P M
AU  - Issa JP
AD  - Department of Morphology, Physiology and Basic Pathology, School of Dentistry of 
      Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil.
FAU - Jordao, A A
AU  - Jordao AA
AD  - Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao 
      Paulo, Sao Paulo, Brazil.
FAU - Shimano, A C
AU  - Shimano AC
AD  - Bioengineering Laboratory, Department of Biomechanics, Medicine and 
      Rehabilitation of the Locomotor System, Ribeirao Preto Medical School, University 
      of Sao Paulo, Sao Paulo, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20160229
PL  - Denmark
TA  - Scand J Med Sci Sports
JT  - Scandinavian journal of medicine & science in sports
JID - 9111504
SB  - IM
MH  - Adipose Tissue
MH  - Animals
MH  - *Body Composition
MH  - *Bone Density
MH  - Cancellous Bone/*pathology
MH  - Cortical Bone/*pathology
MH  - *Diet, High-Fat
MH  - Female
MH  - Ovariectomy
MH  - *Physical Conditioning, Animal
MH  - Rats
MH  - Rats, Wistar
MH  - Tibia/*pathology
MH  - *Weight Gain
OTO - NOTNLM
OT  - Ovariectomy
OT  - bone diseases
OT  - high-fat diet
OT  - metabolic
OT  - microscopy
OT  - treadmill training
EDAT- 2016/03/01 06:00
MHDA- 2017/06/15 06:00
CRDT- 2016/03/01 06:00
PHST- 2016/01/04 00:00 [accepted]
PHST- 2016/03/01 06:00 [pubmed]
PHST- 2017/06/15 06:00 [medline]
PHST- 2016/03/01 06:00 [entrez]
AID - 10.1111/sms.12650 [doi]
PST - ppublish
SO  - Scand J Med Sci Sports. 2017 Feb;27(2):167-176. doi: 10.1111/sms.12650. Epub 2016 
      Feb 29.