PMID- 26928344
OWN - NLM
STAT- MEDLINE
DCOM- 20161031
LR  - 20220310
IS  - 1778-3585 (Electronic)
IS  - 0924-9338 (Linking)
VI  - 34
DP  - 2016 Apr
TI  - Dysfunctional default mode network and executive control network in people with 
      Internet gaming disorder: Independent component analysis under a probability 
      discounting task.
PG  - 36-42
LID - S0924-9338(16)02438-X [pii]
LID - 10.1016/j.eurpsy.2016.01.2424 [doi]
AB  - BACKGROUND: The present study identified the neural mechanism of risky 
      decision-making in Internet gaming disorder (IGD) under a probability discounting 
      task. METHODS: Independent component analysis was used on the functional magnetic 
      resonance imaging data from 19 IGD subjects (22.2 +/- 3.08 years) and 21 healthy 
      controls (HC, 22.8 +/- 3.5 years). RESULTS: For the behavioral results, IGD 
      subjects prefer the risky to the fixed options and showed shorter reaction time 
      compared to HC. For the imaging results, the IGD subjects showed higher 
      task-related activity in default mode network (DMN) and less engagement in the 
      executive control network (ECN) than HC when making the risky decisions. Also, we 
      found the activities of DMN correlate negatively with the reaction time and the 
      ECN correlate positively with the probability discounting rates. CONCLUSIONS: The 
      results suggest that people with IGD show altered modulation in DMN and deficit 
      in executive control function, which might be the reason for why the IGD subjects 
      continue to play online games despite the potential negative consequences.
CI  - Copyright (c) 2016 Elsevier Masson SAS. All rights reserved.
FAU - Wang, L
AU  - Wang L
AD  - Department of Psychology, Zhejiang Normal University, 688 Yingbin Road, Jinhua, 
      Zhejiang Province 321004, PR China.
FAU - Wu, L
AU  - Wu L
AD  - Department of Psychology, University of Konstanz, Konstanz, Germany.
FAU - Lin, X
AU  - Lin X
AD  - Department of Psychology, Zhejiang Normal University, 688 Yingbin Road, Jinhua, 
      Zhejiang Province 321004, PR China; Center for Life Science, Peking University, 
      Beijing, PR China.
FAU - Zhang, Y
AU  - Zhang Y
AD  - Department of Psychology, Zhejiang Normal University, 688 Yingbin Road, Jinhua, 
      Zhejiang Province 321004, PR China.
FAU - Zhou, H
AU  - Zhou H
AD  - Department of Psychology, Zhejiang Normal University, 688 Yingbin Road, Jinhua, 
      Zhejiang Province 321004, PR China.
FAU - Du, X
AU  - Du X
AD  - Department of Physics, Shanghai Key Laboratory of Magnetic Resonance, East China 
      Normal University, Shanghai, PR China.
FAU - Dong, G
AU  - Dong G
AD  - Department of Psychology, Zhejiang Normal University, 688 Yingbin Road, Jinhua, 
      Zhejiang Province 321004, PR China. Electronic address: 
      dongguangheng@zjnu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160227
PL  - England
TA  - Eur Psychiatry
JT  - European psychiatry : the journal of the Association of European Psychiatrists
JID - 9111820
SB  - IM
MH  - Adult
MH  - Behavior, Addictive/*psychology
MH  - Case-Control Studies
MH  - Decision Making
MH  - Executive Function/*physiology
MH  - Female
MH  - Humans
MH  - *Internet
MH  - Male
MH  - Probability
MH  - Reaction Time
MH  - Video Games/*psychology
MH  - Young Adult
OTO - NOTNLM
OT  - Default mode network
OT  - Executive control network
OT  - Independent component analysis
OT  - Internet gaming disorder
OT  - Risky decision-making
EDAT- 2016/03/02 06:00
MHDA- 2016/11/01 06:00
CRDT- 2016/03/02 06:00
PHST- 2015/10/02 00:00 [received]
PHST- 2016/01/23 00:00 [revised]
PHST- 2016/01/26 00:00 [accepted]
PHST- 2016/03/02 06:00 [entrez]
PHST- 2016/03/02 06:00 [pubmed]
PHST- 2016/11/01 06:00 [medline]
AID - S0924-9338(16)02438-X [pii]
AID - 10.1016/j.eurpsy.2016.01.2424 [doi]
PST - ppublish
SO  - Eur Psychiatry. 2016 Apr;34:36-42. doi: 10.1016/j.eurpsy.2016.01.2424. Epub 2016 
      Feb 27.