PMID- 26930959
OWN - NLM
STAT- MEDLINE
DCOM- 20160426
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 33
IP  - 10
DP  - 2015 Oct
TI  - [Simultaneous determination of 16 flavonoids in the ginkgo dietary supplement tea 
      by high performance liquid chromatography-tandem mass spectrometry].
PG  - 1032-9
AB  - A method for the determination of 16 functional components of ginkgo dietary 
      supplement tea such as catechin, vitexin, puerarin, isoflavoues aglycone, 
      silymarin, quercetin, luteolin, apigenin, naringenin, hesperitin dihydrochalcone, 
      kaempferol, hesperitin, isorhamnetin, baicalein, nobiletin and tangeretin by high 
      performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was 
      proposed. The conditions of chromatography and mass spectrometry were optimized. 
      The 16 flavonoids were separated on a C18 chromatographic column with 
      acetonitrile and water (additional 0.1% formic acid) as mobile phases under 
      gradient elution at a flow rate of 0.25 mL/min. The determination was conducted 
      by tandem mass spectrometry in positive ESI mode under multiple reaction 
      monitoring (MRM) mode. Good linearities for all the compounds, with correlation 
      coefficients over 0.996, were acquired. The recoveries were in the range of 70.9% 
      to 100.0% (n = 6), while the relative standard deviations (RSDs) were less than 
      10%. The results showed that the nine flavonoids, which were kaempferol, 
      quercetin, hesperitin, vitexin, luteolin, catechin, apigenin, naringenin and 
      isorhamnetin, were higher in contents among the 16 flavonoids in real samples, 
      and they constituted up to 99.6% of the total flavonoids. The contents of these 
      nine flavonoids can be considered as the quality control index of the ginkgo 
      dietary supplement tea. The method proved to be rapid, selective, sensitive and 
      stable, and it can be applied to control the quality of the ginkgo dietary 
      supplement tea.
FAU - Jiang, Yalan
AU  - Jiang Y
FAU - Huang, Fang
AU  - Huang F
FAU - Wu, Fuhai
AU  - Wu F
FAU - Wu, Huiqin
AU  - Wu H
FAU - Huang, Xiaolan
AU  - Huang X
FAU - Deng, Xin
AU  - Deng X
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Flavonoids)
RN  - 0 (Teas, Herbal)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - *Dietary Supplements
MH  - Flavonoids/*analysis
MH  - *Ginkgo biloba
MH  - Tandem Mass Spectrometry
MH  - Teas, Herbal/*analysis
EDAT- 2016/03/05 06:00
MHDA- 2016/04/27 06:00
CRDT- 2016/03/03 06:00
PHST- 2016/03/03 06:00 [entrez]
PHST- 2016/03/05 06:00 [pubmed]
PHST- 2016/04/27 06:00 [medline]
AID - 10.3724/sp.j.1123.2015.06013 [doi]
PST - ppublish
SO  - Se Pu. 2015 Oct;33(10):1032-9. doi: 10.3724/sp.j.1123.2015.06013.