PMID- 26935711
OWN - NLM
STAT- MEDLINE
DCOM- 20170710
LR  - 20181202
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 26
IP  - 10
DP  - 2016 Oct
TI  - Loop Duodenojejunal Bypass with Sleeve Gastrectomy: Comparative Study with 
      Roux-en-Y Gastric Bypass in Type 2 Diabetic Patients with a BMI <35 kg/m(2), 
      First Year Results.
PG  - 2291-301
LID - 10.1007/s11695-016-2118-z [doi]
AB  - BACKGROUND: Roux-en-Y gastric bypass (RYGB) has shown good diabetes remission in 
      obese patients with type 2 diabetes mellitus (T2DM), but long-term complications 
      were observed. We developed loop duodenojejunal bypass with sleeve gastrectomy 
      (LDJB-SG) to achieve diabetes remission and avoid the drawbacks of RYGB. We 
      compare 1-year results between LDJB-SG and RYGB with body mass index (BMI) 
      <35 kg/m(2) of T2DM patients. METHODS: We conducted a case-matched study of 
      BMI < 35 kg/m(2) T2DM patients who underwent RYGB and LDJB-SG matching on age, 
      BMI, and duration of diabetes. The 1-year surgical results were compared. 
      RESULTS: Sixty patients were included from March 2010 to August 2012. Thirty 
      patients underwent RYGB and 30 underwent LDJB-SG. The operative time (mean +/- SD) 
      and length of stay (median [IQR]) were significantly longer in the LDJB-SG group 
      than in the RYGB group (127.0 +/- 40.2 vs. 105.0 +/- 64.7 min and 3[3, 4] vs. 3[2, 3] 
      days, respectively). There were no statistical differences between the groups in 
      the mean BMI, fasting plasma glucose, and %HbA1c either at baseline or at 1 year. 
      However, these parameters dropped significantly from the preoperative values 
      (p < 0.01). The level of HOMA-%B at 1 year was significantly higher in the 
      LDJB-SG group than in the RYGB group (p = 0.004). The resolution of comorbidities 
      was similar. Late complications seemed higher in the RYGB group (12 vs. 5, 
      p = 0.08). There were no deaths, but two patients in each group required 
      reoperation. CONCLUSIONS: LDJB-SG was comparable to RYGB in terms of weight loss, 
      glycemic control, and comorbidity resolution in BMI <35 kg/m(2) T2DM patients in 
      the short-term.
FAU - Huang, Chih Kun
AU  - Huang CK
AD  - Body Science and Metabolic Disorders International (BMI) Medical Center, China 
      Medical University Hospital, Taichung City, Taiwan.
FAU - Tai, Chi-Ming
AU  - Tai CM
AD  - Bariatric and Metabolic International Surgery Center, E-Da Hospital, Kaohsiung 
      City, Taiwan.
FAU - Chang, Po-Chih
AU  - Chang PC
AD  - Bariatric and Metabolic International Surgery Center, E-Da Hospital, Kaohsiung 
      City, Taiwan.
FAU - Malapan, Kirubakaran
AU  - Malapan K
AD  - Bariatric and Metabolic International Surgery Center, E-Da Hospital, Kaohsiung 
      City, Taiwan.
FAU - Tsai, Ching-Chung
AU  - Tsai CC
AD  - Bariatric and Metabolic International Surgery Center, E-Da Hospital, Kaohsiung 
      City, Taiwan.
FAU - Yolsuriyanwong, Kamthorn
AU  - Yolsuriyanwong K
AD  - Department of Surgery, Songklanagarind Hospital, Prince of Songkla University, 
      Songkhla, Thailand. j-i-n-n@hotmail.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Anastomosis, Surgical/*methods
MH  - Blood Glucose/analysis
MH  - Body Mass Index
MH  - Comorbidity
MH  - Diabetes Mellitus, Type 2/blood/complications/*surgery
MH  - Duodenum/*surgery
MH  - Female
MH  - Gastrectomy/*methods
MH  - *Gastric Bypass
MH  - Humans
MH  - Jejunum/*surgery
MH  - Laparoscopy
MH  - Male
MH  - Middle Aged
MH  - Weight Loss
OTO - NOTNLM
OT  - Loop duodenojejunal bypass
OT  - Obesity
OT  - Roux-en-Y gastric bypass
OT  - Sleeve gastrectomy
OT  - Type 2 diabetes mellitus
EDAT- 2016/03/05 06:00
MHDA- 2017/07/14 06:00
CRDT- 2016/03/04 06:00
PHST- 2016/03/04 06:00 [entrez]
PHST- 2016/03/05 06:00 [pubmed]
PHST- 2017/07/14 06:00 [medline]
AID - 10.1007/s11695-016-2118-z [pii]
AID - 10.1007/s11695-016-2118-z [doi]
PST - ppublish
SO  - Obes Surg. 2016 Oct;26(10):2291-301. doi: 10.1007/s11695-016-2118-z.