PMID- 26939362
OWN - NLM
STAT- MEDLINE
DCOM- 20160504
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 33
IP  - 11
DP  - 2015 Nov
TI  - [Determination of nine estrogenic steroids in milk using matrix solid phase 
      dispersion-ultra performance liquid chromatography with mass spectrometric 
      detector].
PG  - 1163-8
AB  - An analytical method for the multiresidue determination of nine estrogenic 
      steroids in milk was developed by modified matrix solid phase dispersion (MSPD) 
      purification and ultra performance liquid chromatography (UPLC) with mass 
      spectrometric detector (MSD). The sensitivity and accuracy of MSD were better 
      than that of ultraviolet detector. In comparison with traditional mass 
      spectrometry, the merits of MSD were simpler in operation and shorter in starting 
      time (5 min). The results showed that the limits of detection of the compounds 
      with nucleophilic substitution were high in positive ion mode of MSD and were 
      easily affected by environmental conditions. The matrix effects of milk samples 
      reduced from 84%-160% to 80%-121% after MSPD purification. The intraday precision 
      and interday precision of the nine estrogenic steroids were 0.87%-1.78% and 
      1.82%-3.79%, respectively. The average recoveries were 68.7%-94.7%, and the 
      relative standard deviations (RSDs) were less than 10%. The limits of detection 
      (LODs) were 0.5-10 mug/kg. The limits of quantification (LOQ) were 2-20 mug/kg.
FAU - Liu, Hongcheng
AU  - Liu H
FAU - Li, Ning
AU  - Li N
FAU - Lin, Tao
AU  - Lin T
FAU - Shao, Jinliang
AU  - Shao J
FAU - Li, Qiwan
AU  - Li Q
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Estrogens)
RN  - 0 (Steroids)
SB  - IM
MH  - Animals
MH  - Chromatography, High Pressure Liquid
MH  - Estrogens/*analysis
MH  - Food Analysis/*methods
MH  - Mass Spectrometry
MH  - Milk/*chemistry
MH  - Steroids/*analysis
EDAT- 2016/03/05 06:00
MHDA- 2016/05/05 06:00
CRDT- 2016/03/05 06:00
PHST- 2016/03/05 06:00 [entrez]
PHST- 2016/03/05 06:00 [pubmed]
PHST- 2016/05/05 06:00 [medline]
AID - 10.3724/sp.j.1123.2015.06035 [doi]
PST - ppublish
SO  - Se Pu. 2015 Nov;33(11):1163-8. doi: 10.3724/sp.j.1123.2015.06035.