PMID- 26942520 OWN - NLM STAT- MEDLINE DCOM- 20160525 LR - 20181202 IS - 0273-1223 (Print) IS - 0273-1223 (Linking) VI - 73 IP - 5 DP - 2016 TI - Optimization of the synthesis process of an iron oxide nanocatalyst supported on activated carbon for the inactivation of Ascaris eggs in water using the heterogeneous Fenton-like reaction. PG - 1000-9 LID - 10.2166/wst.2015.576 [doi] AB - An experimental design methodology was used to optimize the synthesis of an iron-supported nanocatalyst as well as the inactivation process of Ascaris eggs (Ae) using this material. A factor screening design was used for identifying the significant experimental factors for nanocatalyst support (supported %Fe, (w/w), temperature and time of calcination) and for the inactivation process called the heterogeneous Fenton-like reaction (H2O2 dose, mass ratio Fe/H2O2, pH and reaction time). The optimization of the significant factors was carried out using a face-centered central composite design. The optimal operating conditions for both processes were estimated with a statistical model and implemented experimentally with five replicates. The predicted value of the Ae inactivation rate was close to the laboratory results. At the optimal operating conditions of the nanocatalyst production and Ae inactivation process, the Ascaris ova showed genomic damage to the point that no cell reparation was possible showing that this advanced oxidation process was highly efficient for inactivating this pathogen. FAU - Morales-Perez, Ariadna A AU - Morales-Perez AA AD - Instituto de Ingenieria, Universidad Nacional Autonoma de Mexico, Mexico D.F., Mexico E-mail: rramirezz@iingen.unam.mx. FAU - Maravilla, Pablo AU - Maravilla P AD - Departamento de Ecologia de Agentes Patogenos, Hospital General Dr. Manuel Gea Gonzalez, SSA, Mexico D.F. 14000, Mexico. FAU - Solis-Lopez, Myriam AU - Solis-Lopez M AD - Instituto de Ingenieria, Universidad Nacional Autonoma de Mexico, Mexico D.F., Mexico E-mail: rramirezz@iingen.unam.mx. FAU - Schouwenaars, Rafael AU - Schouwenaars R AD - Departamento de Materiales y Manufactura, DIMEI, Universidad Nacional Autonoma de Mexico, Mexico D.F., Mexico. FAU - Duran-Moreno, Alfonso AU - Duran-Moreno A AD - Facultad de Quimica, Universidad Nacional Autonoma de Mexico, Cd. Universitaria, Coyoacan, Mexico, D. F. 04510, Mexico. FAU - Ramirez-Zamora, Rosa-Maria AU - Ramirez-Zamora RM AD - Instituto de Ingenieria, Universidad Nacional Autonoma de Mexico, Mexico D.F., Mexico E-mail: rramirezz@iingen.unam.mx. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Water Sci Technol JT - Water science and technology : a journal of the International Association on Water Pollution Research JID - 9879497 RN - 0 (Ferric Compounds) RN - 0 (Water Pollutants, Chemical) RN - 059QF0KO0R (Water) RN - 1K09F3G675 (ferric oxide) RN - 7440-44-0 (Carbon) RN - BBX060AN9V (Hydrogen Peroxide) SB - IM MH - Animals MH - Ascaris/*drug effects MH - Carbon/*chemistry MH - Ferric Compounds/*chemistry MH - Hydrogen Peroxide MH - Nanostructures/*chemistry MH - Ovum/*chemistry MH - Oxidation-Reduction MH - Water/*parasitology MH - Water Pollutants, Chemical/analysis MH - Water Purification/methods EDAT- 2016/03/05 06:00 MHDA- 2016/05/26 06:00 CRDT- 2016/03/05 06:00 PHST- 2016/03/05 06:00 [entrez] PHST- 2016/03/05 06:00 [pubmed] PHST- 2016/05/26 06:00 [medline] AID - 10.2166/wst.2015.576 [doi] PST - ppublish SO - Water Sci Technol. 2016;73(5):1000-9. doi: 10.2166/wst.2015.576.