PMID- 26946949
OWN - NLM
STAT- MEDLINE
DCOM- 20170111
LR  - 20170112
IS  - 2042-6313 (Electronic)
IS  - 2042-6305 (Linking)
VI  - 5
IP  - 2
DP  - 2016 Mar
TI  - Comparative effectiveness of primary PCI versus fibrinolytic therapy for ST 
      elevation myocardial infarction: a review of the literature.
PG  - 217-26
LID - 10.2217/cer-2015-0011 [doi]
AB  - AIM: To compare the effectiveness of primary percutaneous coronary intervention 
      (pPCI) and fibrinolytic therapy (FL) for the acute management of ST elevation 
      myocardial infarction (STEMI). METHODS: A review of guidelines and PubMed 
      literature comparing clinical outcomes of patients with STEMI treated with pPCI 
      or FL. RESULTS: Earlier trials reported reduced mortality and reinfarction with 
      pPCI. Recent randomized data suggest similar outcomes for delayed pPCI compared 
      with FL, especially in geographically remote areas. Guidelines recommend pPCI as 
      the preferred reperfusion strategy for STEMI, if available within 120 mins of 
      first medical contact. CONCLUSION: pPCI is the preferred treatment strategy for 
      STEMI. However, FL with subsequent percutaneous coronary intervention remains a 
      viable option for those in rural areas.
FAU - Joy, Eleanor R
AU  - Joy ER
AD  - York Teaching Hospital, NHS Foundation Trust, York, UK.
FAU - Kurian, John
AU  - Kurian J
AD  - Bradford Royal Infirmary, Bradford Teaching Hospital Trust, Bradford, UK.
FAU - Gale, Chris P
AU  - Gale CP
AD  - York Teaching Hospital, NHS Foundation Trust, York, UK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20160307
PL  - England
TA  - J Comp Eff Res
JT  - Journal of comparative effectiveness research
JID - 101577308
SB  - IM
MH  - Comparative Effectiveness Research/*methods/statistics & numerical data
MH  - Humans
MH  - Percutaneous Coronary Intervention/*methods/statistics & numerical data
MH  - ST Elevation Myocardial Infarction/*therapy
MH  - Thrombolytic Therapy/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - ST-elevation myocardial infarction
OT  - fibrinolytic therapy
OT  - primary percutaneous coronary intervention
OT  - thrombolysis
EDAT- 2016/03/08 06:00
MHDA- 2017/01/12 06:00
CRDT- 2016/03/08 06:00
PHST- 2016/03/08 06:00 [entrez]
PHST- 2016/03/08 06:00 [pubmed]
PHST- 2017/01/12 06:00 [medline]
AID - 10.2217/cer-2015-0011 [doi]
PST - ppublish
SO  - J Comp Eff Res. 2016 Mar;5(2):217-26. doi: 10.2217/cer-2015-0011. Epub 2016 Mar 
      7.