PMID- 26950570
OWN - NLM
STAT- MEDLINE
DCOM- 20161230
LR  - 20161231
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 33
IP  - 4
DP  - 2016
TI  - Rapid and sensitive method for the determination of four EU marker polycyclic 
      aromatic hydrocarbons in cereal-based foods using isotope-dilution GC/MS.
PG  - 631-8
LID - 10.1080/19440049.2016.1162032 [doi]
AB  - A rapid and sensitive method has been developed for the determination of the four 
      European Union marker polycyclic aromatic hydrocarbons (PAHs; benz[a]anthracene, 
      chrysene, benzo[b]fluoranthene and benzo[a]pyrene) in some cereal-based foods. 
      The method is based on pressurised liquid extraction (PLE), solid-phase 
      extraction clean-up (SPE) and isotope-dilution gas chromatography with 
      mass-spectrometric detection (GC/MS). The developed method was calibrated for the 
      content range of 0.05-12.5 microg kg(-1) (expressed on a product basis). Recoveries 
      of PAH were monitored in each sample via the recovery of (13)C-labelled PAHs. 
      Recovery values were in the range between 86% and 91%, with relative standard 
      deviations (RSDs) between 5% and 9%. The achieved limits of detection for all 
      analytes were below 0.05 microg kg(-1). The applicability of the method for the 
      analysis of routine samples was studied by the analysis of a set of commercial 
      bread and breakfast cereal samples. In all analysed samples, benzo[a]pyrene (BAP) 
      was the most prevalent PAH with the content between 0.09 and 0.30 microg kg(-1). On 
      average, samples showed low levels of the sum of the four EU marker PAHs (SigmaPAH4) 
      that ranged between 0.11 and 0.22 microg kg(-1) for bread samples and between 0.23 
      and 0.87 microg kg(-1) for breakfast cereal samples. The developed method was found 
      suitable for the determination of PAHs in cereal-based foods like cornflakes and 
      breads with total relative fat contents below 3.5%.
FAU - Kacmaz, Sibel
AU  - Kacmaz S
AD  - a Giresun University , Faculty of Engineering, Department of Food Engineering , 
      Giresun , Turkey.
FAU - Zelinkova, Zuzana
AU  - Zelinkova Z
AD  - b European Commission, Joint Research Centre , Institute for Reference Materials 
      and Measurements , Geel , Belgium.
FAU - Wenzl, Thomas
AU  - Wenzl T
AD  - b European Commission, Joint Research Centre , Institute for Reference Materials 
      and Measurements , Geel , Belgium.
LA  - eng
PT  - Journal Article
DEP - 20160330
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
SB  - IM
MH  - Calibration
MH  - Edible Grain/*chemistry
MH  - European Union
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Limit of Detection
MH  - Polycyclic Aromatic Hydrocarbons/*analysis
MH  - Reference Standards
MH  - Reproducibility of Results
MH  - Uncertainty
OTO - NOTNLM
OT  - Four EU marker PAHs
OT  - GC/MS analysis
OT  - bread
OT  - cornflakes
OT  - method validation
EDAT- 2016/03/08 06:00
MHDA- 2016/12/31 06:00
CRDT- 2016/03/08 06:00
PHST- 2016/03/08 06:00 [entrez]
PHST- 2016/03/08 06:00 [pubmed]
PHST- 2016/12/31 06:00 [medline]
AID - 10.1080/19440049.2016.1162032 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016;33(4):631-8. 
      doi: 10.1080/19440049.2016.1162032. Epub 2016 Mar 30.