PMID- 26957421
OWN - NLM
STAT- MEDLINE
DCOM- 20180409
LR  - 20220410
IS  - 1522-9645 (Electronic)
IS  - 0195-668X (Print)
IS  - 0195-668X (Linking)
VI  - 37
IP  - 40
DP  - 2016 Oct 21
TI  - Imaging- and physiology-guided percutaneous coronary intervention without 
      contrast administration in advanced renal failure: a feasibility, safety, and 
      outcome study.
PG  - 3090-3095
AB  - AIMS: The feasibility, safety, and clinical utility of percutaneous coronary 
      intervention (PCI) without radio-contrast medium in patients with advanced 
      chronic kidney disease (CKD) are unknown. In this series, we investigated a 
      specific strategy for 'zero contrast' PCI with the aims of preserving renal 
      function and preventing the need for renal replacement therapy (RRT) in patients 
      with advanced CKD. METHODS AND RESULTS: A total of 31 patients with advanced CKD 
      [creatinine = 4.2 mg/dL, inter-quartile range (IQR) 3.1-4.8, estimated glomerular 
      filtration rate = 16 +/- 8 mL/min/1.73 m(2)] who had clinical indication for PCI 
      based on a prior minimal contrast coronary angiogram were included. Zero contrast 
      PCI was performed at least 1 week after diagnostic angiography using real-time 
      intravascular ultrasound (IVUS) guidance, with pre- and post-PCI measurements of 
      fractional flow reserve and coronary flow reserve to confirm physiological 
      improvement. This approach resulted in successful PCI, no major adverse 
      cardiovascular events and preservation of renal function without the need for RRT 
      within a follow-up time of 79 days (IQR 33-207) in all patients. CONCLUSION: In 
      patients with advanced CKD who require revascularization, PCI may safely be 
      performed without contrast using IVUS and physiological guidance with high 
      procedural success and without complications.
CI  - Published on behalf of the European Society of Cardiology. All rights reserved. (c) 
      The Author 2016. For permissions please email: journals.permissions@oup.com.
FAU - Ali, Ziad A
AU  - Ali ZA
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA 
      zaa2112@columbia.edu.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Karimi Galougahi, Keyvan
AU  - Karimi Galougahi K
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
FAU - Nazif, Tamim
AU  - Nazif T
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Maehara, Akiko
AU  - Maehara A
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Hardy, Mark A
AU  - Hardy MA
AD  - Department of Surgery, New York Presbyterian Hospital and Columbia University, 
      New York, NY, USA.
FAU - Cohen, David J
AU  - Cohen DJ
AD  - Division of Nephrology, New York Presbyterian Hospital and Columbia University, 
      New York, NY, USA.
FAU - Ratner, Lloyd E
AU  - Ratner LE
AD  - Department of Surgery, New York Presbyterian Hospital and Columbia University, 
      New York, NY, USA.
FAU - Collins, Michael B
AU  - Collins MB
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Moses, Jeffrey W
AU  - Moses JW
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Kirtane, Ajay J
AU  - Kirtane AJ
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Stone, Gregg W
AU  - Stone GW
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Karmpaliotis, Dimitri
AU  - Karmpaliotis D
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
FAU - Leon, Martin B
AU  - Leon MB
AD  - Division of Cardiology, Center for Interventional Vascular Therapy, New York 
      Presbyterian Hospital and Columbia University, New York, NY, USA.
AD  - Cardiovascular Research Foundation, New York, NY, USA.
LA  - eng
GR  - T32 HL007854/HL/NHLBI NIH HHS/United States
PT  - Journal Article
DEP - 20160307
PL  - England
TA  - Eur Heart J
JT  - European heart journal
JID - 8006263
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Coronary Angiography
MH  - Creatinine
MH  - Humans
MH  - *Percutaneous Coronary Intervention
MH  - Renal Insufficiency, Chronic
MH  - Treatment Outcome
PMC - PMC6279210
OTO - NOTNLM
OT  - *Chronic kidney disease
OT  - *Contrast-induced nephropathy
OT  - *Coronary physiology
OT  - *Intravascular ultrasonography
OT  - *Percutaneous coronary intervention
EDAT- 2016/10/30 06:00
MHDA- 2018/04/10 06:00
PMCR- 2017/10/21
CRDT- 2016/03/10 06:00
PHST- 2015/12/21 00:00 [received]
PHST- 2016/02/03 00:00 [accepted]
PHST- 2016/10/30 06:00 [pubmed]
PHST- 2018/04/10 06:00 [medline]
PHST- 2016/03/10 06:00 [entrez]
PHST- 2017/10/21 00:00 [pmc-release]
AID - ehw078 [pii]
AID - 10.1093/eurheartj/ehw078 [doi]
PST - ppublish
SO  - Eur Heart J. 2016 Oct 21;37(40):3090-3095. doi: 10.1093/eurheartj/ehw078. Epub 
      2016 Mar 7.