PMID- 26962935
OWN - NLM
STAT- MEDLINE
DCOM- 20160711
LR  - 20200930
IS  - 1934-6069 (Electronic)
IS  - 1931-3128 (Linking)
VI  - 19
IP  - 3
DP  - 2016 Mar 9
TI  - Actin' on HIV: How Dendritic Cells Spread Infection.
PG  - 267-9
LID - S1931-3128(16)30057-9 [pii]
LID - 10.1016/j.chom.2016.02.016 [doi]
AB  - Dendritic cells (DCs) capture HIV particles and transmit them to CD4 T cells. In 
      a recent article published in Cell, Menager and Littman (2016) perform an shRNA 
      screen in DCs and find that actin nucleation and stabilization regulate HIV 
      uptake and maintain the virus on membrane protrusions for efficient transfer.
CI  - Copyright (c) 2016 Elsevier Inc. All rights reserved.
FAU - Donahue, Daniel A
AU  - Donahue DA
AD  - Institut Pasteur, Department of Virology, Virus & Immunity Unit, Paris 75015, 
      France; CNRS URA 3015, Paris 75015, France. Electronic address: 
      ddonahue@pasteur.fr.
FAU - Schwartz, Olivier
AU  - Schwartz O
AD  - Institut Pasteur, Department of Virology, Virus & Immunity Unit, Paris 75015, 
      France; CNRS URA 3015, Paris 75015, France; Vaccine Research Institute, Creteil 
      94010, France. Electronic address: schwartz@pasteur.fr.
LA  - eng
PT  - Comment
PT  - Journal Article
PL  - United States
TA  - Cell Host Microbe
JT  - Cell host & microbe
JID - 101302316
RN  - 0 (Actins)
SB  - IM
CON - Cell. 2016 Feb 11;164(4):695-709. PMID: 26830877
MH  - Actins/*metabolism
MH  - Dendritic Cells/*immunology
MH  - HIV Infections/*immunology
MH  - HIV-1/*physiology
MH  - Humans
MH  - T-Lymphocytes/*immunology
EDAT- 2016/03/11 06:00
MHDA- 2016/07/12 06:00
CRDT- 2016/03/11 06:00
PHST- 2016/03/11 06:00 [entrez]
PHST- 2016/03/11 06:00 [pubmed]
PHST- 2016/07/12 06:00 [medline]
AID - S1931-3128(16)30057-9 [pii]
AID - 10.1016/j.chom.2016.02.016 [doi]
PST - ppublish
SO  - Cell Host Microbe. 2016 Mar 9;19(3):267-9. doi: 10.1016/j.chom.2016.02.016.