PMID- 2696327
OWN - NLM
STAT- MEDLINE
DCOM- 19900327
LR  - 20171006
IS  - 0386-300X (Print)
IS  - 0386-300X (Linking)
VI  - 43
IP  - 6
DP  - 1989 Dec
TI  - Immune suppression in HTLV-I carriers: a predictive sign of adult T-cell 
      leukemia.
PG  - 317-21
AB  - Suppression of the cellular immune system appears to be a prerequisite for the 
      manifestation of adult T-cell leukemia (ATL). In other words, ATL will develop 
      when impairment of the immune system is caused by the infection of human 
      T-lymphotropic virus type I (HTLV-I). This defect of immune surveillance against 
      virus-infected cells may be a result of the impairment of the function of 
      cytotoxic T-cells (CTLs) specific for the HTLV-I-infected cells. The 
      manifestation of ATL could be predicted by examining the function of CTLs in 
      HTLV-I carriers. A new strategy of prevention and therapy for ATL would include 
      an attempt to restore and fortify the CTL function of the host.
FAU - Taguchi, H
AU  - Taguchi H
AD  - Department of Internal Medicine, Kochi Medical School, Japan.
FAU - Miyoshi, I
AU  - Miyoshi I
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Acta Med Okayama
JT  - Acta medica Okayama
JID - 0417611
SB  - IM
MH  - HTLV-I Infections/*immunology/transmission
MH  - Humans
MH  - Immune Tolerance
MH  - Immunologic Deficiency Syndromes/microbiology
MH  - Leukemia, T-Cell/microbiology
RF  - 36
EDAT- 1989/12/01 00:00
MHDA- 1989/12/01 00:01
CRDT- 1989/12/01 00:00
PHST- 1989/12/01 00:00 [pubmed]
PHST- 1989/12/01 00:01 [medline]
PHST- 1989/12/01 00:00 [entrez]
AID - 10.18926/AMO/30865 [doi]
PST - ppublish
SO  - Acta Med Okayama. 1989 Dec;43(6):317-21. doi: 10.18926/AMO/30865.