PMID- 26966339
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 0422-7638 (Print)
IS  - 2090-9950 (Electronic)
IS  - 0422-7638 (Linking)
VI  - 63
IP  - 1
DP  - 2014 Jan
TI  - Host genome polymorphisms and tuberculosis infection: What we have to say?
PG  - 173-185
AB  - Several epidemiology studies suggest that host genetic factors play important 
      roles in susceptibility, protection and progression of tuberculosis infection. 
      Here we have reviewed the implications of some genetic polymorphisms in pathways 
      related to tuberculosis susceptibility, severity and development. Large 
      case-control studies examining single-nucleotide polymorphisms (SNPs) in genes 
      have been performed in tuberculosis patients in some countries. Polymorphisms in 
      natural resistance-associated macrophage protein 1 (NRAMP1), toll-like receptor 2 
      (TLR2), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-alpha), interleukin-1 
      receptor antagonist (IL-1RA), IL-10, vitamin D receptor (VDR), dendritic 
      cell-specific ICAM-3-grabbing non-integrin (DC-SIGN), monocyte chemoattractant 
      protein-1 (MCP-1), nucleotide oligomerization binding domain 2 (NOD2), 
      interferon-gamma (IFN-gamma), inducible nitric oxide synthase (iNOS), mannose-binding 
      lectin (MBL) and surfactant proteins A (SP-A) have been reviewed. These genes 
      have been variably associated with tuberculosis infection and there is strong 
      evidence indicating that host genetic factors play critical roles in tuberculosis 
      susceptibility, severity and development.
FAU - Khalilullah, Said Alfin
AU  - Khalilullah SA
AD  - Medical Research Unit, School of Medicine Syiah Kuala University, Banda Aceh, 
      Indonesia.
FAU - Harapan, Harapan
AU  - Harapan H
AD  - Medical Research Unit, School of Medicine Syiah Kuala University, Banda Aceh, 
      Indonesia; Tropical Disease Center, School of Medicine Syiah Kuala University, 
      Banda Aceh, Indonesia.
FAU - Hasan, Nabeeh A
AU  - Hasan NA
AD  - Research Affiliate, Centre for Genes, Environment and Health, National Jewish 
      Health, Denver, CO, USA; Computational Bioscience Program, University of 
      Colorado, Anschutz Medical Campus, Aurora, CO, USA.
FAU - Winardi, Wira
AU  - Winardi W
AD  - Medical Research Unit, School of Medicine Syiah Kuala University, Banda Aceh, 
      Indonesia; Graduate Institute of Medical Science, Taipei Medical University, 
      Taipei, Taiwan.
FAU - Ichsan, Ichsan
AU  - Ichsan I
AD  - Medical Research Unit, School of Medicine Syiah Kuala University, Banda Aceh, 
      Indonesia; Tropical Disease Center, School of Medicine Syiah Kuala University, 
      Banda Aceh, Indonesia; Institute of Medical Microbiology and National Reference 
      Center for Systemic Mycosis, University Medical Center Goettingen, Goettingen, 
      Germany.
FAU - Mulyadi, Mulyadi
AU  - Mulyadi M
AD  - Pulmonology Department, School of Medicine, Syiah Kuala University, Banda Aceh, 
      Indonesia.
LA  - eng
GR  - T15 LM009451/LM/NLM NIH HHS/United States
PT  - Journal Article
DEP - 20131217
PL  - Egypt
TA  - Egypt J Chest Dis Tuberc
JT  - The Egyptian journal of chest diseases and tuberculosis
JID - 9892259
PMC - PMC4782973
MID - NIHMS729556
OTO - NOTNLM
OT  - Gene polymorphism
OT  - Mycobacterium tuberculosis
OT  - Tuberculosis development
OT  - Tuberculosis infection
OT  - Tuberculosis protection
OT  - Tuberculosis susceptibility
COIS- Conflict of Interest There is no conflict of interest in writing of this 
      manuscript.
EDAT- 2014/01/01 00:00
MHDA- 2014/01/01 00:01
PMCR- 2016/03/08
CRDT- 2016/03/12 06:00
PHST- 2016/03/12 06:00 [entrez]
PHST- 2014/01/01 00:00 [pubmed]
PHST- 2014/01/01 00:01 [medline]
PHST- 2016/03/08 00:00 [pmc-release]
AID - 10.1016/j.ejcdt.2013.12.002 [doi]
PST - ppublish
SO  - Egypt J Chest Dis Tuberc. 2014 Jan;63(1):173-185. doi: 
      10.1016/j.ejcdt.2013.12.002. Epub 2013 Dec 17.