PMID- 26968137
OWN - NLM
STAT- MEDLINE
DCOM- 20180221
LR  - 20181202
IS  - 1099-1166 (Electronic)
IS  - 0885-6230 (Linking)
VI  - 31
IP  - 9
DP  - 2016 Sep
TI  - Are premorbid abnormal personality traits associated with behavioural and 
      psychological symptoms in dementia?
PG  - 1050-5
LID - 10.1002/gps.4418 [doi]
AB  - OBJECTIVE: The study aims to investigate associations between behavioural and 
      psychological symptoms of dementia (BPSD) and abnormal premorbid personality 
      traits. METHODS: Data were obtained from 217 patients with a diagnosis of 
      probable Alzheimer's disease. Behavioural and psychological symptoms of 
      late-onset dementia were assessed with the Neuropsychiatric Inventory. Premorbid 
      personality traits were assessed using the Standardised Assessment of 
      Personality. Abnormal premorbid personality traits were categorised with 
      Diagnostic and Statistical Manual of Mental Disorders fourth edition and 
      International Statistical Classification of Diseases and Related Health 
      Problems-10 diagnostic criteria for personality disorders. RESULTS: Abnormal 
      premorbid personality traits were associated with increased behavioural and 
      psychological symptoms in dementia. Cluster A (solitary/paranoid) premorbid 
      personality traits were associated with anxiety, depression and hallucinations. 
      Cluster C (anxious/dependent) traits were associated with a syndrome of 
      depression. CONCLUSIONS: The presence of Clusters A (solitary/paranoid) and C 
      (anxious/dependent) abnormal premorbid personality traits seems to affect the 
      expression of certain behavioural and psychological symptoms in dementia, 
      depression in particular. Copyright (c) 2016 John Wiley & Sons, Ltd.
CI  - Copyright (c) 2016 John Wiley & Sons, Ltd.
FAU - Prior, Jack
AU  - Prior J
AD  - Department of Old Age Psychiatry, Godalming, Surrey, UK.
FAU - Abraham, Rajesh
AU  - Abraham R
AD  - Department of Old Age Psychiatry, Godalming, Surrey, UK.
FAU - Nicholas, Helen
AU  - Nicholas H
AD  - Department of Psychology, University of Worcester, Worcester, UK.
FAU - Chan, Tom
AU  - Chan T
AD  - University of Surrey, Guildford, UK.
FAU - Vanvlymen, Jeremy
AU  - Vanvlymen J
AD  - University of Surrey, Guildford, UK.
FAU - Lovestone, Simon
AU  - Lovestone S
AD  - Department of Psychiatry, University of Oxford, Oxford, UK.
FAU - Boothby, Harry
AU  - Boothby H
AD  - Department of Old Age Psychiatry, Godalming, Surrey, UK.
LA  - eng
GR  - Medical Research Council/United Kingdom
PT  - Journal Article
DEP - 20160310
PL  - England
TA  - Int J Geriatr Psychiatry
JT  - International journal of geriatric psychiatry
JID - 8710629
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aggression
MH  - Alzheimer Disease/psychology
MH  - Anxiety/complications
MH  - *Behavior
MH  - Cluster Analysis
MH  - Dementia/*psychology
MH  - Depression/complications
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Female
MH  - Humans
MH  - Irritable Mood
MH  - Male
MH  - *Personality
MH  - Personality Disorders/*complications/psychology
MH  - Psychotic Disorders/*complications/psychology
OTO - NOTNLM
OT  - BPSD (behavioural and psychological symptoms in dementia)
OT  - Dementia
OT  - personality
EDAT- 2016/03/13 06:00
MHDA- 2018/02/22 06:00
CRDT- 2016/03/13 06:00
PHST- 2015/09/14 00:00 [received]
PHST- 2015/12/03 00:00 [accepted]
PHST- 2016/03/13 06:00 [entrez]
PHST- 2016/03/13 06:00 [pubmed]
PHST- 2018/02/22 06:00 [medline]
AID - 10.1002/gps.4418 [doi]
PST - ppublish
SO  - Int J Geriatr Psychiatry. 2016 Sep;31(9):1050-5. doi: 10.1002/gps.4418. Epub 2016 
      Mar 10.