PMID- 26972961 OWN - NLM STAT- MEDLINE DCOM- 20161213 LR - 20181202 IS - 1872-8227 (Electronic) IS - 0168-8227 (Linking) VI - 113 DP - 2016 Mar TI - Serum irisin concentrations were increased after transient continuous subcutaneous insulin infusion in type 2 diabetes mellitus patients. PG - 44-7 LID - S0168-8227(16)00079-6 [pii] LID - 10.1016/j.diabres.2016.01.030 [doi] AB - Irisin, identified as a novel myokine, plays an important role in improving metabolic disorders, including type 2 diabetes mellitus (T2DM). In this interventional study, we investigated the alteration of serum irisin levels in T2DM subjects after transient continuous subcutaneous insulin infusion (CSII) treatment. CI - Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved. FAU - Li, Liang AU - Li L AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China. FAU - Rampersad, Sharvan AU - Rampersad S AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China. FAU - Wang, Xingchun AU - Wang X AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China. FAU - Cheng, Xiaoyun AU - Cheng X AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China. Electronic address: chengxiaoyun0210@163.com. FAU - Qu, Shen AU - Qu S AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China. LA - eng PT - Comparative Study PT - Journal Article DEP - 20160202 PL - Ireland TA - Diabetes Res Clin Pract JT - Diabetes research and clinical practice JID - 8508335 RN - 0 (Biomarkers) RN - 0 (FNDC5 protein, human) RN - 0 (Fibronectins) RN - 0 (Hypoglycemic Agents) RN - 0 (Insulin) SB - IM MH - Adult MH - Biomarkers/*blood MH - Case-Control Studies MH - Diabetes Mellitus, Type 2/*blood/drug therapy MH - Drug Administration Schedule MH - Female MH - Fibronectins/*blood MH - Humans MH - Hypoglycemic Agents/*administration & dosage MH - Infusions, Subcutaneous MH - Insulin/*administration & dosage MH - Male MH - Middle Aged OTO - NOTNLM OT - CSII OT - HbA1c OT - Irisin OT - Lipid profiles OT - T2DM EDAT- 2016/03/15 06:00 MHDA- 2016/12/15 06:00 CRDT- 2016/03/15 06:00 PHST- 2015/08/13 00:00 [received] PHST- 2016/01/17 00:00 [revised] PHST- 2016/01/22 00:00 [accepted] PHST- 2016/03/15 06:00 [entrez] PHST- 2016/03/15 06:00 [pubmed] PHST- 2016/12/15 06:00 [medline] AID - S0168-8227(16)00079-6 [pii] AID - 10.1016/j.diabres.2016.01.030 [doi] PST - ppublish SO - Diabetes Res Clin Pract. 2016 Mar;113:44-7. doi: 10.1016/j.diabres.2016.01.030. Epub 2016 Feb 2.