PMID- 26976026
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160315
LR  - 20200930
IS  - 1976-8710 (Print)
IS  - 2005-0720 (Electronic)
IS  - 1976-8710 (Linking)
VI  - 9
IP  - 1
DP  - 2016 Mar
TI  - The Healing Effects of Autologous Mucosal Grafts in Experimentally Injured Rabbit 
      Maxillary Sinuses.
PG  - 44-50
LID - 10.21053/ceo.2016.9.1.44 [doi]
AB  - OBJECTIVES: Healing processes of the nose and paranasal sinuses are quite 
      complex, and poorly understood. In this study, we aimed to compare the effect of 
      mucosal autologous grafts on the degenerated rabbit maxillary sinus mucosa with 
      spontaneous wound healing. It is hypothesized that mucosal grafts will enhance 
      ciliogenesis and improve the morphology of regenerated cilia. METHODS: Ten female 
      New Zealand rabbits were included in the study. They underwent external maxillary 
      sinus surgery through a transcutaneous approach. A total of 20 maxillary sinuses 
      were randomly divided into 2 groups: 'spontaneous healing group' and 'autologous 
      graft group.' The animals were sacrificed at the 14th day after the surgery. 
      Scanning electron microscope (SEM), and light microscope were used for the 
      evaluation. RESULTS: Cellular composition of the graft group is better than the 
      spontaneous healing group. The graft group had larger areas covered with ciliary 
      epithelium than the spontaneous healing group, and the mean length of the cilias 
      were also longer. Additionally, there were wider cilia with abnormal morphology 
      areas in the spontaneous healing group. CONCLUSION: In our opinion, covering of 
      the denuded areas with a graft improves re-epithelization, and may prevent the 
      early complications after sinus surgeries.
FAU - Topdag, Murat
AU  - Topdag M
AD  - Department of Otorhinolaryngology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey.
FAU - Kara, Ahmet
AU  - Kara A
AD  - Department of Otorhinolaryngology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey.
FAU - Konuk, Esma
AU  - Konuk E
AD  - Department of Histology and Embryology, Akdeniz University Faculty of Medicine, 
      Antalya, Turkey.
FAU - Demir, Necdet
AU  - Demir N
AD  - Department of Histology and Embryology, Akdeniz University Faculty of Medicine, 
      Antalya, Turkey.
FAU - Ozturk, Murat
AU  - Ozturk M
AD  - Department of Otorhinolaryngology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey.
FAU - Caliskan, Sebla
AU  - Caliskan S
AD  - Department of Otorhinolaryngology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey.
FAU - Topdag, Deniz Ozlem
AU  - Topdag DO
AD  - Department of Otorhinolaryngology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey.
FAU - Ulubil, Arif
AU  - Ulubil A
AD  - Department of Otorhinolaryngology, Acibadem University Faculty of Medicine, 
      Istanbul, Turkey.
FAU - Keskin, Ibrahim Gurkan
AU  - Keskin IG
AD  - Department of Otorhinolaryngology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey.
FAU - Iseri, Mete
AU  - Iseri M
AD  - Department of Otorhinolaryngology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20160307
PL  - Korea (South)
TA  - Clin Exp Otorhinolaryngol
JT  - Clinical and experimental otorhinolaryngology
JID - 101474010
PMC - PMC4792244
OTO - NOTNLM
OT  - Maxillary Sinus
OT  - Nasal Mucosa
OT  - Rabbits
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2016/03/16 06:00
MHDA- 2016/03/16 06:01
PMCR- 2016/03/01
CRDT- 2016/03/16 06:00
PHST- 2014/12/12 00:00 [received]
PHST- 2015/02/18 00:00 [revised]
PHST- 2015/02/23 00:00 [accepted]
PHST- 2016/03/16 06:00 [entrez]
PHST- 2016/03/16 06:00 [pubmed]
PHST- 2016/03/16 06:01 [medline]
PHST- 2016/03/01 00:00 [pmc-release]
AID - ceo-2016-9-1-44 [pii]
AID - 10.21053/ceo.2016.9.1.44 [doi]
PST - ppublish
SO  - Clin Exp Otorhinolaryngol. 2016 Mar;9(1):44-50. doi: 10.21053/ceo.2016.9.1.44. 
      Epub 2016 Mar 7.