PMID- 26976237
OWN - NLM
STAT- MEDLINE
DCOM- 20170228
LR  - 20181113
IS  - 1878-0938 (Electronic)
IS  - 1553-8389 (Print)
IS  - 1878-0938 (Linking)
VI  - 17
IP  - 4
DP  - 2016 Jun
TI  - Cardiac output determination using a widely available direct continuous oxygen 
      consumption measuring device: a practical way to get back to the gold standard.
PG  - 256-61
LID - S1553-8389(16)30050-1 [pii]
LID - 10.1016/j.carrev.2016.02.013 [doi]
AB  - BACKGROUND: Accurate assessment of cardiac output (CO) is essential for the 
      hemodynamic assessment of valvular heart disease. Estimation of oxygen 
      consumption (VO2) and thermodilution (TD) are employed in many cardiac 
      catheterization laboratories (CCL) given the historically cumbersome nature of 
      direct continuous VO2 measurement, the "gold standard" for this technique. A 
      portable facemask device simplifies the direct continuous measurement of VO2, 
      allowing for relatively rapid and continuous assessment of CO. METHODS AND 
      MATERIALS: Thirty consecutive patients undergoing right heart catheterization had 
      simultaneous determination of CO by both direct continuous and assumed VO2 and 
      TD. Assessments were only made when a plateau of VO2 had occurred. All 
      measurements of direct continuous and assumed VO2, as well as, TD CO were 
      obtained in triplicate. RESULTS: Direct continuous VO2 CO and assumed VO2 CO 
      correlated poorly (R=0.57; ICC=0.59). Direct continuous VO2 CO and TD CO also 
      correlated poorly (R=0.51; ICC=0.60). Repeated direct continuous VO2 CO 
      measurements were extremely correlated and reproducible [(R=0.93; ICC=0.96) 
      suggesting that this was the most reliable measurement of CO. CONCLUSIONS: CO 
      calculated from direct continuous VO2 measurement varies substantially from both 
      assumed VO2 and TD based CO, which are widely used in most CCL. These differences 
      may significantly impact the CO measurements. Furthermore, continuous, rather 
      than average, measurement of VO2 appears to give highly reproducible results.
CI  - Copyright (c) 2016 Elsevier Inc. All rights reserved.
FAU - Fanari, Zaher
AU  - Fanari Z
AD  - Division of Cardiology, University of Kansas School of Medicine, Kansas City, KS, 
      USA. Electronic address: zfanari@gmail.com.
FAU - Grove, Matthew
AU  - Grove M
AD  - Section of Cardiology, Carolina East Medical Center, New Bern, NC, USA.
FAU - Rajamanickam, Anitha
AU  - Rajamanickam A
AD  - Division of Cardiology, Mount Sinai Heart, New York, NY, USA.
FAU - Hammami, Sumaya
AU  - Hammami S
AD  - Division of Cardiology, University of Kansas School of Medicine, Kansas City, KS, 
      USA; Section of Cardiology, Christiana Care Health System, Newark, DE, USA.
FAU - Walls, Cassie
AU  - Walls C
AD  - Section of Cardiology, Christiana Care Health System, Newark, DE, USA.
FAU - Kolm, Paul
AU  - Kolm P
AD  - Value Institute, Christiana Care Health System, Newark, DE, USA.
FAU - Saltzberg, Mitchell
AU  - Saltzberg M
AD  - Section of Cardiology, Christiana Care Health System, Newark, DE, USA.
FAU - Weintraub, William S
AU  - Weintraub WS
AD  - Section of Cardiology, Christiana Care Health System, Newark, DE, USA; Value 
      Institute, Christiana Care Health System, Newark, DE, USA.
FAU - Doorey, Andrew J
AU  - Doorey AJ
AD  - Section of Cardiology, Christiana Care Health System, Newark, DE, USA; Value 
      Institute, Christiana Care Health System, Newark, DE, USA.
LA  - eng
GR  - U54 GM104941/GM/NIGMS NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
DEP - 20160227
PL  - United States
TA  - Cardiovasc Revasc Med
JT  - Cardiovascular revascularization medicine : including molecular interventions
JID - 101238551
SB  - IM
MH  - *Breath Tests/instrumentation
MH  - Cardiac Catheterization
MH  - *Cardiac Output
MH  - Heart Function Tests/instrumentation/*standards
MH  - Heart Valve Diseases/*diagnosis/physiopathology
MH  - Humans
MH  - *Oxygen Consumption
MH  - Predictive Value of Tests
MH  - Reproducibility of Results
MH  - Thermodilution/*standards
MH  - Time Factors
PMC - PMC4912455
MID - NIHMS764209
OTO - NOTNLM
OT  - Assumed oxygen consumption
OT  - Cardiac output
OT  - Direct continuous oxygen consumption
OT  - Thermodilution
EDAT- 2016/03/16 06:00
MHDA- 2017/03/01 06:00
PMCR- 2017/06/01
CRDT- 2016/03/16 06:00
PHST- 2016/01/01 00:00 [received]
PHST- 2016/02/15 00:00 [revised]
PHST- 2016/02/24 00:00 [accepted]
PHST- 2016/03/16 06:00 [entrez]
PHST- 2016/03/16 06:00 [pubmed]
PHST- 2017/03/01 06:00 [medline]
PHST- 2017/06/01 00:00 [pmc-release]
AID - S1553-8389(16)30050-1 [pii]
AID - 10.1016/j.carrev.2016.02.013 [doi]
PST - ppublish
SO  - Cardiovasc Revasc Med. 2016 Jun;17(4):256-61. doi: 10.1016/j.carrev.2016.02.013. 
      Epub 2016 Feb 27.