PMID- 26986048
OWN - NLM
STAT- MEDLINE
DCOM- 20170531
LR  - 20171230
IS  - 1527-1315 (Electronic)
IS  - 0033-8419 (Linking)
VI  - 280
IP  - 3
DP  - 2016 Sep
TI  - Prognostic Value of Cardiac MR Imaging for Preoperative Assessment of Patients 
      with Severe Functional Tricuspid Regurgitation.
PG  - 723-34
LID - 10.1148/radiol.2016151556 [doi]
AB  - Purpose To explore the prognostic value of cardiac magnetic resonance (MR) 
      imaging in predicting postoperative cardiac death in patients with severe 
      functional tricuspid regurgitation (TR). Materials and Methods This study was 
      approved by the institutional review board, and written informed consent was 
      obtained from all patients. Prospectively collected data included cardiac MR 
      images, New York Heart Association (NYHA) functional class, a comprehensive 
      laboratory test, and clinical events over the follow-up period in 75 consecutive 
      patients (61 women and 14 men; mean age +/- standard deviation, 59 years +/- 9) 
      undergoing corrective surgery for severe functional TR. Cox proportional hazards 
      models were used to assess the association between cardiac MR parameters and 
      outcomes. Results During a median follow-up period of 57 months (range, 21-82 
      months), cardiac mortality and all-cause mortality were 17.3% and 26.7%, 
      respectively, with a surgical mortality of 6.7%. Cardiac death risk was lower 
      with a higher right ventricular (RV) ejection fraction (EF) on cardiac MR images 
      (hazard ratio per 5% higher EF = 0.790, P = .048). By adjusting for confounding 
      variables, RV EF remained a significant predictor for cardiac death (P < .05) and 
      major postoperative cardiac events (P < .05). The area under the receiver 
      operating characteristic curve (AUC) confirmed the incremental role of RV EF on 
      cardiac MR images in the prediction of postoperative cardiac death (AUC, 
      0.681-0.771; P = .041) and major postoperative cardiac events (AUC, 0.660-0.745; 
      P = .044) on top of NYHA class. RV end-systolic volume index was also 
      independently associated with these outcomes but failed to increase the AUC 
      significantly. Conclusion Preoperative assessment of cardiac MR imaging-based RV 
      EF provides independent and incremental prognostic information in patients 
      undergoing corrective surgery for severe functional TR. ((c)) RSNA, 2016 Online 
      supplemental material is available for this article.
FAU - Park, Jun-Bean
AU  - Park JB
AUID- ORCID: 0000-0003-4053-8713
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Kim, Hyung-Kwan
AU  - Kim HK
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Jung, Ji-Hyun
AU  - Jung JH
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Klem, Igor
AU  - Klem I
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Yoon, Yeonyee E
AU  - Yoon YE
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Lee, Seung-Pyo
AU  - Lee SP
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Park, Eun-Ah
AU  - Park EA
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Hwang, Ho-Young
AU  - Hwang HY
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Lee, Whal
AU  - Lee W
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Kim, Kyung-Hwan
AU  - Kim KH
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Kim, Yong-Jin
AU  - Kim YJ
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Cho, Goo-Yeong
AU  - Cho GY
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Kim, Ki-Bong
AU  - Kim KB
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Sohn, Dae-Won
AU  - Sohn DW
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
FAU - Ahn, Hyuk
AU  - Ahn H
AD  - From the Departments of Internal Medicine (J.B.P., H.K.K., J.H.J., Y.E.Y., 
      S.P.L., Y.J.K., G.Y.C., D.W.S.), Radiology (E.A.P., W.L.), and Cardiovascular 
      Thoracic Surgery (H.Y.H., K.H.K., K.B.K., H.A.), Seoul National University 
      College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South Korea; and 
      Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke 
      University Medical Center, Durham, NC (I.K.).
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160317
PL  - United States
TA  - Radiology
JT  - Radiology
JID - 0401260
SB  - IM
MH  - Echocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Prospective Studies
MH  - Reproducibility of Results
MH  - Survival Rate
MH  - Treatment Outcome
MH  - Tricuspid Valve Insufficiency/*diagnostic imaging/*physiopathology/surgery
EDAT- 2016/03/18 06:00
MHDA- 2017/06/01 06:00
CRDT- 2016/03/18 06:00
PHST- 2016/03/18 06:00 [entrez]
PHST- 2016/03/18 06:00 [pubmed]
PHST- 2017/06/01 06:00 [medline]
AID - 10.1148/radiol.2016151556 [doi]
PST - ppublish
SO  - Radiology. 2016 Sep;280(3):723-34. doi: 10.1148/radiol.2016151556. Epub 2016 Mar 
      17.