PMID- 26988312
OWN - NLM
STAT- MEDLINE
DCOM- 20170106
LR  - 20220420
IS  - 1758-1877 (Electronic)
IS  - 1758-1869 (Linking)
VI  - 6
IP  - 3
DP  - 2016
TI  - The opioid epidemic and the long-term opioid therapy for chronic noncancer pain 
      revisited: a transatlantic perspective.
PG  - 249-63
LID - 10.2217/pmt.16.5 [doi]
AB  - The rise of opioid prescriptions and associated deaths ('opioid epidemic') in 
      North America has evoked worldwide discussions on the long-term efficacy and 
      safety of long-term opioid therapy (LtOT) for chronic noncancer pain (CNCP). We 
      discuss if the opioid epidemic is a real worldwide or a more North American 
      phenomenon. We consider reasons of the opioid epidemic. We highlight differences 
      in the appraisal of the evidence of recent systematic reviews on LtOT for CNCP of 
      US and European authors. We discuss similarities and differences of recent North 
      American and European guidelines on LtOT for chronic CNCP. We point out potential 
      indications and contraindications of LtOT in CNCP syndromes.
FAU - Hauser, Winfried
AU  - Hauser W
AD  - Internal Medicine 1, Klinikum Saarbrucken, Winterberg 1, D-66119 Saarbrucken, 
      Germany.
AD  - Department of Psychosomatic Medicine & Psychotherapy, Technische Universitat 
      Munchen, Ismaningerstrabetae 22, D-81675 Munchen, Germany.
FAU - Petzke, Frank
AU  - Petzke F
AD  - Day Clinic & Out Patient Department Pain Therapy, Universitatsmedizin Gottingen, 
      D-37075 Gottingen, Germany.
FAU - Radbruch, Lukas
AU  - Radbruch L
AD  - Department of Palliative Medicine, University Hospital Bonn, Center of Palliative 
      Care, Malteser Hospital Seliger Gerhard Bonn/Rhein-Sieg, D-53127 Bonn, Germany.
FAU - Tolle, Thomas R
AU  - Tolle TR
AD  - Department of Neurology, Technische Universitat Munchen, Ismaningerstrabetae 22, 
      D-81675 Munchen, Germany.
LA  - eng
PT  - Journal Article
DEP - 20160318
PL  - England
TA  - Pain Manag
JT  - Pain management
JID - 101555934
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Analgesics, Opioid/*adverse effects
MH  - Chronic Pain/drug therapy/*epidemiology
MH  - *Epidemics
MH  - Europe/epidemiology
MH  - Humans
MH  - North America/epidemiology
MH  - Opioid-Related Disorders/*epidemiology
MH  - Risk Factors
OTO - NOTNLM
OT  - chronic noncancer pain
OT  - guidelines
OT  - long-term opioid therapy
OT  - misuse and addiction
OT  - mortality
OT  - opioid abuse
OT  - opioids
OT  - systematic review
EDAT- 2016/03/19 06:00
MHDA- 2017/01/07 06:00
CRDT- 2016/03/19 06:00
PHST- 2016/03/19 06:00 [entrez]
PHST- 2016/03/19 06:00 [pubmed]
PHST- 2017/01/07 06:00 [medline]
AID - 10.2217/pmt.16.5 [doi]
PST - ppublish
SO  - Pain Manag. 2016;6(3):249-63. doi: 10.2217/pmt.16.5. Epub 2016 Mar 18.