PMID- 26988382 OWN - NLM STAT- MEDLINE DCOM- 20170614 LR - 20170614 IS - 0151-9638 (Print) IS - 0151-9638 (Linking) VI - 143 IP - 5 DP - 2016 May TI - [Bowel-associated dermatosis-arthritis syndrome during ulcerative colitis: A rare extra-intestinal sign of inflammatory bowel disease]. PG - 377-81 LID - S0151-9638(16)00095-8 [pii] LID - 10.1016/j.annder.2016.02.009 [doi] AB - INTRODUCTION: Bowel-associated dermatosis-arthritis syndrome (BADAS) is characterized by combined pustular skin eruption and arthralgia. It may be associated with inflammatory bowel disease or bowel bypass surgery. We report a case of BADAS in a patient with ulcerative colitis. CASE REPORT: A 39-year-old woman was being treated for a severe flare-up of ulcerative colitis present over the preceding 2 months and treated with prednisone, azathioprine and cyclosporine. She was also presenting a cutaneous eruption and arthralgia that had begun three days earlier. Dermatological examination revealed profuse vesicular and pustular lesions. Biopsy specimens showed mature neutrophilic infiltrate within the dermis. A diagnosis of BADAS was made and the same treatment was maintained. Systemic symptoms were resolved but the vesicular lesions were superseded by hypertrophic scars. DISCUSSION: Bowel-associated dermatosis-arthritis syndrome consists of a vesiculopustular eruption associated with arthralgia and/or arthritis and fever, as was the case in our patient. The histological picture is characterized by abundant neutrophilic infiltrate in the superficial dermis. The clinical and histological features and the course of BADAS allow this entity to be classified within the spectrum of neutrophilic dermatoses. Treatment chiefly involves systemic corticosteroids. CI - Copyright (c) 2016 Elsevier Masson SAS. All rights reserved. FAU - Aounallah, A AU - Aounallah A AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. Electronic address: amina_aounallah@yahoo.fr. FAU - Zerriaa, S AU - Zerriaa S AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Ksiaa, M AU - Ksiaa M AD - Service de gastro-enterologie, hopital universitaire Sahloul, route Ceinture Cite Sahloul, 4054 Sousse, Tunisie. FAU - Jaziri, H AU - Jaziri H AD - Service de gastro-enterologie, hopital universitaire Sahloul, route Ceinture Cite Sahloul, 4054 Sousse, Tunisie. FAU - Boussofara, L AU - Boussofara L AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Ghariani, N AU - Ghariani N AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Mokni, S AU - Mokni S AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Saidi, W AU - Saidi W AD - Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Sriha, B AU - Sriha B AD - Laboratoire d'anatomie et de cytologie pathologiques, hopital Fahat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Belajouza, C AU - Belajouza C AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Denguezli, M AU - Denguezli M AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. FAU - Nouira, R AU - Nouira R AD - Universite de Sousse, avenue Khlifa Karoui, 4054 Sousse, Tunisie; Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. LA - fre PT - Case Reports PT - Journal Article TT - Syndrome arthro-cutane lors d'une rectocolite ulcero-hemorragique : une manifestation extra-intestinale rare des maladies inflammatoires de l'intestin. DEP - 20160314 PL - France TA - Ann Dermatol Venereol JT - Annales de dermatologie et de venereologie JID - 7702013 SB - IM MH - Adult MH - Arthralgia/*etiology MH - Colitis, Ulcerative/*complications MH - Female MH - Humans MH - Rare Diseases MH - Skin Diseases, Vesiculobullous/*etiology OTO - NOTNLM OT - Dermatoses neutrophiliques OT - Dermatosis-arthritis syndrome OT - Inflammatory bowel disease OT - Maladies inflammatoires chroniques de l'intestin OT - Neutrophilic dermatoses OT - Pyoderma gangrenosum OT - Rectocolite ulcero-hemorragique OT - Syndrome arthro-cutane OT - Ulcerative colitis EDAT- 2016/03/19 06:00 MHDA- 2017/06/15 06:00 CRDT- 2016/03/19 06:00 PHST- 2015/08/03 00:00 [received] PHST- 2015/11/20 00:00 [revised] PHST- 2016/02/03 00:00 [accepted] PHST- 2016/03/19 06:00 [entrez] PHST- 2016/03/19 06:00 [pubmed] PHST- 2017/06/15 06:00 [medline] AID - S0151-9638(16)00095-8 [pii] AID - 10.1016/j.annder.2016.02.009 [doi] PST - ppublish SO - Ann Dermatol Venereol. 2016 May;143(5):377-81. doi: 10.1016/j.annder.2016.02.009. Epub 2016 Mar 14.