PMID- 26989399
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160318
LR  - 20181113
IS  - 1664-3828 (Print)
IS  - 1664-5502 (Electronic)
IS  - 1664-5502 (Linking)
VI  - 6
IP  - 2
DP  - 2016 Feb
TI  - Prognostic Implications of Acute Renal Impairment among ST Elevation Myocardial 
      Infarction Patients with Preserved Left Ventricular Function.
PG  - 143-9
LID - 10.1159/000443621 [doi]
AB  - BACKGROUND: Only limited data is present regarding the incidence and prognostic 
      implications of acute kidney injury (AKI) in ST elevation myocardial infarction 
      (STEMI) patients with preserved left ventricular (LV) function in the primary 
      percutaneous coronary intervention (PCI) era. METHODS: We conducted a 
      retrospective study of 842 consecutive STEMI patients with preserved LV function 
      (ejection fraction >/=50%, assessed by echocardiography) who underwent primary PCI 
      between January 2008 and January 2015. AKI was defined as an increase of >/=0.3 
      mg/dl in serum creatinine within 48 h following admission. Patients were assessed 
      for all-cause mortality up to 5 years. RESULTS: Fifty-two patients (6.2%) 
      developed AKI. Patients with AKI were older, had impaired baseline renal 
      function, and presented more often with heart failure throughout their 
      hospitalization. Patients with AKI had a higher 5-year all-cause mortality (13.4 
      vs. 2.4%, p < 0.001). Compared to patients with no AKI, the adjusted hazard ratio 
      for all-cause mortality was 2.64 (95% CI 1.25-5.56, p = 0.01). CONCLUSIONS: Among 
      STEMI patients with preserved LV function undergoing primary PCI, AKI is 
      associated with a higher long-term mortality.
FAU - Shacham, Yacov
AU  - Shacham Y
AD  - Departments of Cardiology, Tel Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Gal-Oz, Amir
AU  - Gal-Oz A
AD  - Departments of Nephrology, Tel Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Ben-Shoshan, Jeremy
AU  - Ben-Shoshan J
AD  - Departments of Cardiology, Tel Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Keren, Gad
AU  - Keren G
AD  - Departments of Cardiology, Tel Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Arbel, Yaron
AU  - Arbel Y
AD  - Departments of Cardiology, Tel Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
LA  - eng
PT  - Journal Article
DEP - 20160203
PL  - Switzerland
TA  - Cardiorenal Med
JT  - Cardiorenal medicine
JID - 101554863
PMC - PMC4789877
OTO - NOTNLM
OT  - Acute kidney injury
OT  - Ejection fraction
OT  - Percutaneous coronary intervention
OT  - ST elevation myocardial infarction
EDAT- 2016/03/19 06:00
MHDA- 2016/03/19 06:01
PMCR- 2016/02/03
CRDT- 2016/03/19 06:00
PHST- 2015/09/07 00:00 [received]
PHST- 2015/12/10 00:00 [accepted]
PHST- 2016/03/19 06:00 [entrez]
PHST- 2016/03/19 06:00 [pubmed]
PHST- 2016/03/19 06:01 [medline]
PHST- 2016/02/03 00:00 [pmc-release]
AID - crm-0006-0143 [pii]
AID - 10.1159/000443621 [doi]
PST - ppublish
SO  - Cardiorenal Med. 2016 Feb;6(2):143-9. doi: 10.1159/000443621. Epub 2016 Feb 3.