PMID- 26990739
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20180313
IS  - 1873-376X (Electronic)
IS  - 1570-0232 (Linking)
VI  - 1017-1018
DP  - 2016 Apr 1
TI  - Comparison of two extraction methods for the determination of 135 pesticides in 
      Corydalis Rhizoma, Chuanxiong Rhizoma and Angelicae Sinensis Radix by liquid 
      chromatography-triple quadrupole-mass spectrometry. Application to the roots and 
      rhizomes of Chinese herbal medicines.
PG  - 233-240
LID - S1570-0232(16)30134-9 [pii]
LID - 10.1016/j.jchromb.2016.03.003 [doi]
AB  - In this study, two simple pretreatment methods were comprehensively evaluated for 
      the determination of 135 pesticide residues in roots and rhizomes of Chinese 
      herbal medicines (CHMs). The studied methodologies are (a) solid-phase extraction 
      (SPE) and (b) Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS). For SPE, 
      extraction solvents, SPE cartridges and types and volume of eluent were accessed 
      and optimized. For QuEChERS, different versions, acetic acid concentration and 
      dispersive solid-phase extraction (dSPE) sorbent materials were tested. SPE and 
      QuEChERS were estimated in recovery range, the number of pesticides that were 
      recovered ranging from 90% to 110% and expenses in Corydalis Rhizoma, Chuanxiong 
      Rhizoma and Angelicae Sinensis Radix. QuEChERS method showed better performance 
      than SPE. The method showed good linearity over the range assayed 0.9986-0.9999 
      (1-80ng/mL for 124 pesticides, 1-50ng/mL for 10 pesticides, 1-20ng/mL for 
      satisfar). The matrix effect was compensated by matrix-based calibration curves 
      with internal standard. The average recoveries of all pesticides were ranging 
      from 70% to 120% at three levels of 10, 50 and 100ng/g with relative standard 
      deviations less than 20%. The limits of quantification of the 135 pesticides in 
      three matrices were 1-5ng/g, which were below the maximum residue levels (MRLs) 
      established by the European Union. The verified QuEChERS method was successfully 
      applied to the analysis of 65 actual samples from eight different types of roots 
      and rhizomes of CHMs. Angelicae Sinensis Radix was the most susceptible to 
      pesticides among these samples, and the most frequently detected pesticide was 
      carbendazim with levels below MRLs. Metalaxyl, phorate, atrazine, diniconazole, 
      coumaphos and paclobutrazol were also detected in some samples.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Liu, Jie
AU  - Liu J
AD  - School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe 
      District, Shenyang 110016, China; Pharmaceutical Analysis Institute, Tasly 
      Holding Group Academy, Tianjin 300402, China.
FAU - Tong, Ling
AU  - Tong L
AD  - Pharmaceutical Analysis Institute, Tasly Holding Group Academy, Tianjin 300402, 
      China.
FAU - Li, Dongxiang
AU  - Li D
AD  - Pharmaceutical Analysis Institute, Tasly Holding Group Academy, Tianjin 300402, 
      China.
FAU - Meng, Wenting
AU  - Meng W
AD  - Pharmaceutical Analysis Institute, Tasly Holding Group Academy, Tianjin 300402, 
      China.
FAU - Sun, Wanyang
AU  - Sun W
AD  - School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe 
      District, Shenyang 110016, China; Pharmaceutical Analysis Institute, Tasly 
      Holding Group Academy, Tianjin 300402, China.
FAU - Zhao, Yunli
AU  - Zhao Y
AD  - School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe 
      District, Shenyang 110016, China. Electronic address: yunli76@163.com.
FAU - Yu, Zhiguo
AU  - Yu Z
AD  - School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe 
      District, Shenyang 110016, China. Electronic address: zhiguo-yu@163.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160307
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Calibration
MH  - Chromatography, Liquid/*methods
MH  - Limit of Detection
MH  - Mass Spectrometry/*methods
MH  - Pesticide Residues/*analysis
MH  - Plant Roots/chemistry
MH  - Reproducibility of Results
MH  - Rhizome/*chemistry
OTO - NOTNLM
OT  - Chinese herbal medicines
OT  - Pesticides
OT  - QuEChERS
OT  - Solid-phase extraction
OT  - UHPLC-MS/MS
EDAT- 2016/03/19 06:00
MHDA- 2016/12/15 06:00
CRDT- 2016/03/19 06:00
PHST- 2015/11/19 00:00 [received]
PHST- 2016/03/01 00:00 [revised]
PHST- 2016/03/02 00:00 [accepted]
PHST- 2016/03/19 06:00 [entrez]
PHST- 2016/03/19 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - S1570-0232(16)30134-9 [pii]
AID - 10.1016/j.jchromb.2016.03.003 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Apr 1;1017-1018:233-240. doi: 
      10.1016/j.jchromb.2016.03.003. Epub 2016 Mar 7.