PMID- 27000738 OWN - NLM STAT- MEDLINE DCOM- 20160912 LR - 20181202 IS - 1532-8686 (Electronic) IS - 0037-1963 (Linking) VI - 53 IP - 2 DP - 2016 Apr TI - Supportive care in alternative donor transplantation. PG - 129-35 LID - S0037-1963(16)00012-3 [pii] LID - 10.1053/j.seminhematol.2016.01.011 [doi] AB - Alternative donor hematopoietic cell transplantation (HCT) using umbilical cord blood, haploidentical or mismatched unrelated donors is a viable option for patients without human leukocyte antigen (HLA)-identical sibling or matched unrelated donors. The same principles of supportive care as conventional graft sources apply to alternative donor HCT recipients. However, there are some unique supportive care issues related to post-transplant complications, engraftment, graft-versus-host disease, immune reconstitution, and infections that are unique to each of the three alternative graft sources, both in the early and late post-transplant periods. This review discusses the supportive care issues relevant to this population and their management. CI - Copyright (c) 2016 Elsevier Inc. All rights reserved. FAU - Fu, Shuang AU - Fu S AD - Department of Hematology-Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH; Blood & Marrow Transplant Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH. FAU - Majhail, Navneet S AU - Majhail NS AD - Blood & Marrow Transplant Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH. Electronic address: majhain@ccf.org. LA - eng PT - Journal Article PT - Review DEP - 20160115 PL - United States TA - Semin Hematol JT - Seminars in hematology JID - 0404514 SB - IM MH - Fetal Blood MH - Graft vs Host Disease/etiology MH - Haploidy MH - *Hematopoietic Stem Cell Transplantation/adverse effects MH - Humans MH - Unrelated Donors OTO - NOTNLM OT - Complications OT - Haploidentical transplantation OT - Treatment-related mortality Graft-versus-host disease OT - Umbilical cord blood transplantation EDAT- 2016/03/24 06:00 MHDA- 2016/09/13 06:00 CRDT- 2016/03/23 06:00 PHST- 2016/03/23 06:00 [entrez] PHST- 2016/03/24 06:00 [pubmed] PHST- 2016/09/13 06:00 [medline] AID - S0037-1963(16)00012-3 [pii] AID - 10.1053/j.seminhematol.2016.01.011 [doi] PST - ppublish SO - Semin Hematol. 2016 Apr;53(2):129-35. doi: 10.1053/j.seminhematol.2016.01.011. Epub 2016 Jan 15.