PMID- 27001795
OWN - NLM
STAT- MEDLINE
DCOM- 20180129
LR  - 20180420
IS  - 1464-360X (Electronic)
IS  - 1101-1262 (Linking)
VI  - 26
IP  - 5
DP  - 2016 Oct
TI  - Health-care-related adverse events leading to admission in older individuals: 
      incidence, predictive factors and consequences.
PG  - 743-748
AB  - BACKGROUND: Older individuals are particularly prone to suffer 
      health-care-related adverse events (AEs); they often have more comorbidity and, 
      thus, require more health-care. Since our society is ageing, insight into AEs 
      leading to hospital admissions is necessary. We aimed to assess the incidence, 
      predictive factors and consequences of AEs leading to admission in older 
      individuals. METHODS: We performed a retrospective cohort study of all older 
      patients (>/=65 years) who were admitted through the emergency department (ED) to 
      the department of internal medicine in the last week of every month in 2011. We 
      retrieved the incidence and possible predictive factors for AEs leading to 
      admission and mortality (both in-hospital and within 28 days after discharge). 
      The control group consisted of older patients admitted because of other reasons. 
      RESULTS: In the study period, there were 262 admissions, of which 106 (40.5%) 
      were because of an AE. The most common AE was medication-related (55.7%). 
      Predictive factors of admission because of an AE were the number of medications 
      used [odds ratio (OR) 1.16 per medication, 95% confidence intervals (CI) 
      1.08-1.25] and dependency in instrumental activities of daily living (IADL) (OR 
      0.35, 95% CI 0.14-0.91). Both in-hospital mortality and mortality within 28 days 
      after discharge were lower in the AE group (5.7% vs. 16.0%, P = 0.01, and 0 vs. 
      6.9%, P < 0.05, respectively). CONCLUSION: Admissions through the ED to the 
      department of internal medicine of older patients are often because of AEs 
      (40.5%), with medication use being the greatest culprit. Surprisingly, mortality 
      was lower in the AE group. The number of medications used (positive) and IADL 
      dependency (negative) were predictive factors for being admitted because of an 
      AE.
CI  - (c) The Author 2016. Published by Oxford University Press on behalf of the European 
      Public Health Association. All rights reserved.
FAU - Magdelijns, Fabienne J H
AU  - Magdelijns FJ
AD  - Division of General Medicine, Department of Internal Medicine, Maastricht 
      University Medical Centre, Maastricht University, Maastricht, The Netherlands 
      fabienne.magdelijns@mumc.nl.
FAU - van Avesaath, R E M
AU  - van Avesaath RE
AD  - Division of General Medicine, Department of Internal Medicine, Maastricht 
      University Medical Centre, Maastricht University, Maastricht, The Netherlands.
FAU - Pijpers, E
AU  - Pijpers E
AD  - Division of General Medicine, Department of Internal Medicine, Maastricht 
      University Medical Centre, Maastricht University, Maastricht, The Netherlands.
AD  - Section of Clinical Geriatric Medicine, Maastricht University Medical Centre, 
      Maastricht University, Maastricht, the Netherlands.
FAU - Stehouwer, C D A
AU  - Stehouwer CD
AD  - Division of General Medicine, Department of Internal Medicine, Maastricht 
      University Medical Centre, Maastricht University, Maastricht, The Netherlands.
AD  - Cardiovascular Research Institute Maastricht, Maastricht University Medical 
      Centre, Maastricht University, Maastricht, the Netherlands.
FAU - Stassen, P M
AU  - Stassen PM
AD  - Division of General Medicine, Department of Internal Medicine, Maastricht 
      University Medical Centre, Maastricht University, Maastricht, The Netherlands.
AD  - School of CAPHRI, Maastricht, the Netherlands.
AD  - Section of Acute Medicine, Maastricht University Medical Centre, Maastricht 
      University, Maastricht, the Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20160321
PL  - England
TA  - Eur J Public Health
JT  - European journal of public health
JID - 9204966
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Cohort Studies
MH  - Emergency Service, Hospital/*statistics & numerical data
MH  - Female
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Medication Adherence/*statistics & numerical data
MH  - Netherlands
MH  - Odds Ratio
MH  - Patient Readmission/*statistics & numerical data
MH  - Retrospective Studies
EDAT- 2016/03/24 06:00
MHDA- 2018/01/30 06:00
CRDT- 2016/03/23 06:00
PHST- 2016/03/24 06:00 [pubmed]
PHST- 2018/01/30 06:00 [medline]
PHST- 2016/03/23 06:00 [entrez]
AID - ckw021 [pii]
AID - 10.1093/eurpub/ckw021 [doi]
PST - ppublish
SO  - Eur J Public Health. 2016 Oct;26(5):743-748. doi: 10.1093/eurpub/ckw021. Epub 
      2016 Mar 21.