PMID- 27005016
OWN - NLM
STAT- MEDLINE
DCOM- 20170717
LR  - 20170817
IS  - 1365-229X (Electronic)
IS  - 0009-9260 (Linking)
VI  - 71
IP  - 6
DP  - 2016 Jun
TI  - Manual adjustment of tube voltage from 120 to 100 kVp during abdominal CT in 
      patients with body weights </=75 kg: assessment of image quality and radiation dose 
      in a prospective, randomised trial.
PG  - 615.e1-6
LID - S0009-9260(16)00090-8 [pii]
LID - 10.1016/j.crad.2016.02.014 [doi]
AB  - AIM: To assess image quality and radiation dose in patients with body weights </=75 
      kg undergoing abdominal computed tomography (CT) with a tube voltage of either 
      120 or 100 kVp. MATERIALS AND METHODS: Eighty patients weighing </=75 kg were 
      prospectively assigned to receive either 120 or 100 kVp abdominal CT in the 
      portal-venous phase. Attenuation values of abdominal organs and image noise were 
      measured, and the contrast-to-noise ratios (CNRs) were calculated. Subjective 
      image quality was assessed by three independent radiologists. Radiation exposure 
      was assessed by size-specific dose estimate (SSDE). RESULTS: The mean attenuation 
      of the kidney increased by 20% at 100 kVp (p<0.0001), and the mean image noise 
      was 27% higher in the 100 kVp (p=0.003). The CNR did not significantly differ 
      between the groups (120 kVp, 6.6+/-2.8; 100 kVp, 7.4+/-3.6; p=0.26). Except for 
      subjective image noise (p<0.001), no other subjective quality parameters (e.g., 
      contrast, artefacts) were significantly different between the two groups (p 
      between 0.094 and 0.761). The mean SSDE in the 100-kVp group (9.8+/-1.8 mGy) was 
      reduced by 19% compared to the 120-kVp group (12.1+/-1.8 mGy; p<0.0001). 
      CONCLUSION: Manual reduction of tube voltage from the standard 120 to 100 kVp for 
      portal-venous phase CT in patients with body weights </=75 kg resulted in a 19% 
      dose reduction while maintaining objective and subjective image quality.
CI  - Copyright (c) 2016 The Royal College of Radiologists. Published by Elsevier Ltd. 
      All rights reserved.
FAU - Zaehringer, C
AU  - Zaehringer C
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, 
      Switzerland.
FAU - Euler, A
AU  - Euler A
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, 
      Switzerland.
FAU - Karwacki, G M
AU  - Karwacki GM
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, 
      Switzerland.
FAU - Hohmann, J
AU  - Hohmann J
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, 
      Switzerland.
FAU - Pansini, M
AU  - Pansini M
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, 
      Switzerland.
FAU - Szucs-Farkas, Z
AU  - Szucs-Farkas Z
AD  - Department of Diagnostic Radiology, Hospital Center of Biel, Biel, Switzerland.
FAU - Schindera, S T
AU  - Schindera ST
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, 
      Switzerland. Electronic address: sebastian.schindera@usb.ch.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20160319
PL  - England
TA  - Clin Radiol
JT  - Clinical radiology
JID - 1306016
SB  - IM
MH  - *Body Weight
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multidetector Computed Tomography/*methods
MH  - Prospective Studies
MH  - *Radiation Dosage
MH  - Radiation Protection/*methods
MH  - Radiographic Image Interpretation, Computer-Assisted/*methods
MH  - Radiography, Abdominal/*methods
MH  - Radiometry/methods
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2016/03/24 06:00
MHDA- 2017/07/18 06:00
CRDT- 2016/03/24 06:00
PHST- 2016/01/04 00:00 [received]
PHST- 2016/02/05 00:00 [revised]
PHST- 2016/02/14 00:00 [accepted]
PHST- 2016/03/24 06:00 [entrez]
PHST- 2016/03/24 06:00 [pubmed]
PHST- 2017/07/18 06:00 [medline]
AID - S0009-9260(16)00090-8 [pii]
AID - 10.1016/j.crad.2016.02.014 [doi]
PST - ppublish
SO  - Clin Radiol. 2016 Jun;71(6):615.e1-6. doi: 10.1016/j.crad.2016.02.014. Epub 2016 
      Mar 19.