PMID- 27007835
OWN - NLM
STAT- MEDLINE
DCOM- 20170117
LR  - 20220408
IS  - 0125-877X (Print)
IS  - 0125-877X (Linking)
VI  - 34
IP  - 2
DP  - 2016 Jun
TI  - Minimal clinical important difference (MCID) of the Thai Chronic Urticaria 
      Quality of Life Questionnaire (CU-Q2oL).
PG  - 137-45
LID - 10.12932/AP0674.34.2.2016 [doi]
AB  - BACKGROUND: Chronic urticaria (CU) has negative impacts on patients' daily lives. 
      The Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) evaluates quality 
      of life impairment attitudes among chronic urticaria patients. Although the 
      CU-Q2oL has been validated in several languages, the minimal clinical important 
      difference (MCID) of the CU-Q2oL has never been determined. OBJECTIVE: This study 
      aimed to investigate the validity, reliability, responsiveness to change, and 
      MCID of the Thai CU-Q2oL. METHODS: The Thai CU-Q2oL was translated with 
      permission from the authors of the original Italian version. The Thai CU-Q2oL, 
      the validated Thai Dermatology Life Quality Index (DLQI), and the Urticaria 
      Activity Score were assessed for 166 patients to evaluate validity and internal 
      consistency. The three questionnaires were then administered to 124 patients to 
      determine the test-retest reliability, responsiveness, and MCID of the Thai 
      CU-Q2oL. RESULTS: The Thai CU-Q2oL contained only three domains, whereas the 
      Italian version revealed six domains. Nevertheless, the total variance of the 
      Thai CU-Q2oL (60.5%) was very close to that of the Italian version (60.0%). The 
      validity of the Thai CU-Q2oL was shown by strong correlations between CU-Q2oL and 
      DLQI scores. The Thai CU-Q2oL also had high internal consistency and test-retest 
      reliability. Distribution-based, receiver operating characteristic analysis, and 
      anchor-based approaches yielded MCID values of 3.9-8.0, 15, and 21.1, 
      respectively. CONCLUSIONS: The Thai CU-Q2oL is a valid and reliable instrument. 
      We propose that a difference in the Thai CU-Q2oL score of 15 (MCID) is the 
      smallest change patients perceive as a meaningful improvement.
FAU - Kulthanan, Kanokvalai
AU  - Kulthanan K
AD  - Department of Dermatology Faculty of Medicine Siriraj Hospital Mahidol University 
      Bangkok Thailand.
FAU - Chularojanamontri, Leena
AU  - Chularojanamontri L
FAU - Tuchinda, Papapit
AU  - Tuchinda P
FAU - Rujitharanawong, Chuda
AU  - Rujitharanawong C
FAU - Baiardini, Ilaria
AU  - Baiardini I
FAU - Braido, Fulvio
AU  - Braido F
LA  - eng
PT  - Journal Article
PT  - Validation Study
PL  - Thailand
TA  - Asian Pac J Allergy Immunol
JT  - Asian Pacific journal of allergy and immunology
JID - 8402034
SB  - IM
MH  - Activities of Daily Living
MH  - Adult
MH  - Chronic Disease
MH  - Cost of Illness
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - *Quality of Life
MH  - Reproducibility of Results
MH  - *Surveys and Questionnaires
MH  - Thailand
MH  - Translating
MH  - Urticaria/complications/diagnosis/*psychology
EDAT- 2016/03/24 06:00
MHDA- 2017/01/18 06:00
CRDT- 2016/03/24 06:00
PHST- 2016/03/24 06:00 [entrez]
PHST- 2016/03/24 06:00 [pubmed]
PHST- 2017/01/18 06:00 [medline]
AID - 10.12932/AP0674.34.2.2016 [doi]
PST - ppublish
SO  - Asian Pac J Allergy Immunol. 2016 Jun;34(2):137-45. doi: 
      10.12932/AP0674.34.2.2016.