PMID- 27011945
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160325
LR  - 20220321
IS  - 2250-1541 (Print)
IS  - 1947-2714 (Electronic)
IS  - 1947-2714 (Linking)
VI  - 8
IP  - 1
DP  - 2016 Jan
TI  - Association of Comorbid and Metabolic Factors with Optimal Control of Type 2 
      Diabetes Mellitus.
PG  - 31-9
LID - 10.4103/1947-2714.175197 [doi]
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM) is a poorly controlled epidemic 
      worldwide that demands active research into mitigation of the factors that are 
      associated with poor control. AIMS: The study was to determine the factors 
      associated with suboptimal glycemic control. MATERIALS AND METHODS: Electronic 
      medical records of 263 adult patients with T2DM in our suburban internal medicine 
      office were reviewed. Patients were divided into two groups: Group 1 [optimal 
      diabetes control with glycosylated hemoglobin (HbA1c) of 7% or less] and Group 2 
      (suboptimal diabetes control with HbA1c greater than 7%). The influence of 
      factors such as age, gender, race, social history, comorbid conditions, 
      gestational diabetes, family history of diabetes, diabetes management, statin 
      use, aspirin use, angiotensin convertase enzyme inhibitor (ACE-I) or angiotensin 
      receptor blocker (ARB) use, body mass index (BMI), blood pressures, lipid 
      profile, and urine microalbumin level were analyzed in the two groups. RESULTS: 
      In the suboptimal diabetes control group (N = 119), the majority (86.6%) of the 
      patients were 41-80 years old. Factors associated with the suboptimal control 
      were male gender [odds ratio (OR) 2.6, 95% confidence interval (CI), 
      1.579-4.321], Asian ethnicity (OR 1.4, 95% CI, 0.683-3.008), history of 
      peripheral arterial disease (PAD; OR 3.9, 95% CI, 1.017-14.543), history of 
      congestive heart failure (CHF; OR 3.9, 95% CI, 1.017-14.543), elevated 
      triglycerides (OR 1.004, 95% CI, 1.000-1.007), and elevated urine microalbumin 
      level of 30 mg/24 h or above (OR 4.5, 95% CI, 2.446-8.380). Patients with 
      suboptimal diabetes control had a 3.8 times greater odds (95% CI, 1.493-6.885) of 
      receiving the insulin and oral hypoglycemic agent together. CONCLUSIONS: In adult 
      patients with T2DM, male gender, Asian ethnicity, CHF, PAD, management with 
      insulin along with oral hypoglycemic agents, hypertriglyceridemia, and 
      microalbuminuria were associated with suboptimal control.
FAU - Roy, Satyajeet
AU  - Roy S
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Sherman, Anthony
AU  - Sherman A
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Monari-Sparks, Mary Joan
AU  - Monari-Sparks MJ
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Schweiker, Olga
AU  - Schweiker O
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Jain, Navjot
AU  - Jain N
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Sims, Etty
AU  - Sims E
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Breda, Michelle
AU  - Breda M
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Byraiah, Gita P
AU  - Byraiah GP
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Belecanech, Ryan George
AU  - Belecanech RG
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Coletta, Michael Domenic
AU  - Coletta MD
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Barrios, Cristian Javier
AU  - Barrios CJ
AD  - Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA.
FAU - Hunter, Krystal
AU  - Hunter K
AD  - Department of Biostatistics, Cooper Research Institute, Cooper Medical School of 
      Rowan University, Camden, New Jersey, USA.
FAU - Gaughan, John P
AU  - Gaughan JP
AD  - Department of Biostatistics, Cooper Research Institute, Cooper Medical School of 
      Rowan University, Camden, New Jersey, USA.
LA  - eng
PT  - Journal Article
PL  - India
TA  - N Am J Med Sci
JT  - North American journal of medical sciences
JID - 101521411
PMC - PMC4784181
OTO - NOTNLM
OT  - Asian ethnicity
OT  - congestive heart failure (CHF)
OT  - hypertriglyceridemia
OT  - male gender
OT  - microalbuminuria
OT  - peripheral arterial disease (PAD)
OT  - suboptimal control of type 2 diabetes
OT  - type 2 diabetes mellitus (T2DM)
EDAT- 2016/03/25 06:00
MHDA- 2016/03/25 06:01
PMCR- 2016/01/01
CRDT- 2016/03/25 06:00
PHST- 2016/03/25 06:00 [entrez]
PHST- 2016/03/25 06:00 [pubmed]
PHST- 2016/03/25 06:01 [medline]
PHST- 2016/01/01 00:00 [pmc-release]
AID - NAJMS-8-31 [pii]
AID - 10.4103/1947-2714.175197 [doi]
PST - ppublish
SO  - N Am J Med Sci. 2016 Jan;8(1):31-9. doi: 10.4103/1947-2714.175197.