PMID- 27016025 OWN - NLM STAT- MEDLINE DCOM- 20171226 LR - 20200306 IS - 1522-2594 (Electronic) IS - 0740-3194 (Print) IS - 0740-3194 (Linking) VI - 77 IP - 3 DP - 2017 Mar TI - Accelerated phase contrast flow imaging with direct complex difference reconstruction. PG - 1036-1048 LID - 10.1002/mrm.26184 [doi] AB - PURPOSE: To propose and evaluate a new model-based reconstruction method for highly accelerated phase-contrast magnetic resonance imaging (PC-MRI) with sparse sampling. THEORY AND METHODS: This work presents a new constrained reconstruction method based on low-rank and sparsity constraints to accelerate PC-MRI. More specifically, we formulate the image reconstruction problem into separate reconstructions of flow-reference image sequence and complex differences. We then utilize the joint partial separability and sparsity constraints to enable high quality reconstruction from highly undersampled (k,t)-space data. We further integrate the proposed method with ESPIRiT based parallel imaging model to effectively handle multichannel acquisition. RESULTS: The proposed method was evaluated with in vivo data acquired from both 2D and 3D PC flow imaging experiments, and compared with several state-of-the-art methods. Experimental results demonstrate that the proposed method leads to more accurate velocity reconstruction from highly undersampled (k,t)-space data, and particularly superior capability of capturing the peak velocity of blood flow. In terms of flow visualization, blood flow patterns obtained from the proposed reconstruction also exhibit better agreement with those obtained from the fully sampled reference. CONCLUSION: The proposed method achieves improved accuracy over several state-of-the-art methods for velocity reconstruction with highly accelerated (k,t)-space data. Magn Reson Med 77:1036-1048, 2017. (c) 2016 International Society for Magnetic Resonance in Medicine. CI - (c) 2016 International Society for Magnetic Resonance in Medicine. FAU - Sun, Aiqi AU - Sun A AD - Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. FAU - Zhao, Bo AU - Zhao B AD - Department of Electrical and Computer Engineering and Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA. FAU - Ma, Ke AU - Ma K AD - Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. FAU - Zhou, Zechen AU - Zhou Z AD - Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. FAU - He, Le AU - He L AD - Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. FAU - Li, Rui AU - Li R AD - Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. FAU - Yuan, Chun AU - Yuan C AD - Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. AD - Vascular Imaging Lab, Department of Radiology, University of Washington, Seattle, Washington, USA. LA - eng GR - R01 EB013695/EB/NIBIB NIH HHS/United States GR - R01 HL103609/HL/NHLBI NIH HHS/United States PT - Evaluation Study PT - Journal Article DEP - 20160326 PL - United States TA - Magn Reson Med JT - Magnetic resonance in medicine JID - 8505245 SB - IM MH - Adult MH - *Algorithms MH - Aorta/anatomy & histology/*physiology MH - Blood Flow Velocity/*physiology MH - Female MH - Humans MH - Image Enhancement/*methods MH - Image Interpretation, Computer-Assisted/*methods MH - Magnetic Resonance Angiography/*methods MH - Male MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Subtraction Technique MH - Young Adult PMC - PMC5734924 MID - NIHMS914140 OTO - NOTNLM OT - complex differences OT - low-rank modeling OT - model-based reconstruction OT - parallel imaging OT - partial separability OT - phase-contrast MRI OT - sparsity EDAT- 2016/03/27 06:00 MHDA- 2017/12/27 06:00 PMCR- 2017/12/18 CRDT- 2016/03/27 06:00 PHST- 2015/05/07 00:00 [received] PHST- 2016/01/31 00:00 [revised] PHST- 2016/02/05 00:00 [accepted] PHST- 2016/03/27 06:00 [pubmed] PHST- 2017/12/27 06:00 [medline] PHST- 2016/03/27 06:00 [entrez] PHST- 2017/12/18 00:00 [pmc-release] AID - 10.1002/mrm.26184 [doi] PST - ppublish SO - Magn Reson Med. 2017 Mar;77(3):1036-1048. doi: 10.1002/mrm.26184. Epub 2016 Mar 26.