PMID- 27020595 OWN - NLM STAT- MEDLINE DCOM- 20170410 LR - 20221207 IS - 1473-2300 (Electronic) IS - 0300-0605 (Print) IS - 0300-0605 (Linking) VI - 44 IP - 3 DP - 2016 Jun TI - Assessment of associations between ischaemic attacks in patients with type 2 diabetes mellitus and air concentrations of particulate matter <2.5 mum. PG - 639-55 LID - 10.1177/0300060516631702 [doi] AB - OBJECTIVE: To investigate the relationship between air concentrations of fine particulate matter <2.5 microm in diameter (PM2.5) and ischaemic attacks in high-risk elderly patients (aged >/=60 years). METHODS: This retrospective data analysis study extracted clinical data from an electronic medical chart system and environmental air quality data from the Ministry of the Environment Atmospheric Environmental Regional Observation System. Patients were stratified into four groups according to whether or not they had type 2 diabetes mellitus (T2DM) and/or an ischaemic attack (i.e. cerebral infarctions and myocardial infarctions) during the 2-year study period. Analysis of the combined clinical and environmental data produced the odds ratio for the likelihood of experiencing an ischaemic attack. RESULTS: Clinical data were collected from 94 647 patients. On days when the air temperature was >/=25℃ and PM2.5 concentration was >/=20microg/m(3), an ischaemic attack was more likely to occur in the T2DM group than in the group without T2DM. An ischaemic attack was more likely to occur 2 days after an increase in the PM2.5 concentration compared with the same day as and 3-6 days after the increase. CONCLUSION: The results of this study confirmed an association between PM2.5 and ischaemic attacks in high-risk patients. CI - (c) The Author(s) 2016. FAU - Hoshino, Takayuki AU - Hoshino T AD - Department of Clinical Research and Informatics, National Centre for Global Health and Medicine, Tokyo, Japan Department of Psychiatry, Akagi-kohgen Hospital, Shibukawa, Gunma, Japan Department of Internal Medicine, Gohyakuyama Clinic, Takasaki, Gunma, Japan Graduate School of Environmental Information, Teikyo Heisei University, Tokyo, Japan hoshino1133@hotmail.co.jp. FAU - Hoshino, Ayami AU - Hoshino A AD - Department of Internal Medicine, Gohyakuyama Clinic, Takasaki, Gunma, Japan. FAU - Nishino, Junya AU - Nishino J AD - Graduate School of Environmental Information, Teikyo Heisei University, Tokyo, Japan. LA - eng PT - Journal Article DEP - 20160328 PL - England TA - J Int Med Res JT - The Journal of international medical research JID - 0346411 RN - 0 (Air Pollutants) RN - 0 (Particulate Matter) SB - IM MH - Aged MH - Air Pollutants/*adverse effects MH - Asian People MH - Brain Ischemia/*etiology MH - Demography MH - Diabetes Mellitus, Type 2/*complications MH - Female MH - Humans MH - Male MH - Myocardial Ischemia/*etiology MH - Odds Ratio MH - *Particle Size MH - Particulate Matter/*adverse effects MH - Temperature PMC - PMC5536720 OTO - NOTNLM OT - Heart attack OT - brain attack OT - ischaemic attack OT - particulate matter <2.5 microm OT - type 2 diabetes mellitus EDAT- 2016/03/30 06:00 MHDA- 2017/04/11 06:00 PMCR- 2016/06/01 CRDT- 2016/03/30 06:00 PHST- 2015/10/13 00:00 [received] PHST- 2016/01/14 00:00 [accepted] PHST- 2016/03/30 06:00 [entrez] PHST- 2016/03/30 06:00 [pubmed] PHST- 2017/04/11 06:00 [medline] PHST- 2016/06/01 00:00 [pmc-release] AID - 0300060516631702 [pii] AID - 10.1177_0300060516631702 [pii] AID - 10.1177/0300060516631702 [doi] PST - ppublish SO - J Int Med Res. 2016 Jun;44(3):639-55. doi: 10.1177/0300060516631702. Epub 2016 Mar 28.