PMID- 27021495
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20220408
IS  - 1708-8305 (Electronic)
IS  - 1195-1982 (Linking)
VI  - 23
IP  - 3
DP  - 2016 Mar
TI  - Comparative study of adverse events after yellow fever vaccination between 
      elderly and non-elderly travellers: questionnaire survey in Japan over a 1-year 
      period.
LID - taw012 [pii]
LID - 10.1093/jtm/taw012 [doi]
AB  - BACKGROUND: A live attenuated yellow fever (YF) vaccination is required of all 
      travellers visiting countries where YF virus is endemic. Although the risk of 
      serious adverse events (AEs) after YF vaccination is known to be greater in 
      elderly people than in younger people, information about other AEs among elderly 
      travellers is lacking. METHODS: A prospective observational questionnaire study 
      was conducted to investigate the occurrence of AEs after YF vaccination in 
      travellers who attended a designated YF vaccination centre in Tokyo, Japan, from 
      1 November 2011 to 31 October 2012. A questionnaire enquiring about any AEs 
      experienced in the 2 weeks following YF vaccination was distributed to all 
      vaccinees enrolled in this study, and responses were collected subsequently by 
      mail or phone. For child vaccinees, their parents were allowed to respond in 
      their stead. RESULTS: Of the 1298 vaccinees who received the YF vaccine, 1044 
      (80.4%) were enrolled in the present study and 666 (63.8%) responded to the 
      questionnaire. Of these 666 respondents, 370 (55.6%) reported AEs, of which 258 
      (38.7%) were systemic and 230 (34.5%) were local. No severe AEs associated with 
      YF vaccination were reported. Elderly vaccinees (aged >/=60 years) reported fewer 
      total AEs than those aged <60 years (42.9% vs 60.3%;P < 0.001). CONCLUSION: Our 
      study showed that fewer general AEs after yellow vaccination reported among 
      elderly vaccinees than among non-elderly vaccinees. These results could provide 
      supplementary information for judging the adaptation of vaccination in elderly 
      travellers.
CI  - (c) International Society of Travel Medicine, 2016. All rights reserved. Published 
      by Oxford University Press. For permissions, please e-mail: 
      journals.permissions@oup.com.
FAU - Tanizaki, Ryutaro
AU  - Tanizaki R
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Ujiie, Mugen
AU  - Ujiie M
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan infinite_u@hotmail.com.
FAU - Hori, Narumi
AU  - Hori N
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Kanagawa, Shuzo
AU  - Kanagawa S
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Kutsuna, Satoshi
AU  - Kutsuna S
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Takeshita, Nozomi
AU  - Takeshita N
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Hayakawa, Kayoko
AU  - Hayakawa K
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Kato, Yasuyuki
AU  - Kato Y
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Ohmagari, Norio
AU  - Ohmagari N
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160328
PL  - England
TA  - J Travel Med
JT  - Journal of travel medicine
JID - 9434456
RN  - 0 (Yellow Fever Vaccine)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Child
MH  - Female
MH  - Humans
MH  - Japan
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Parents
MH  - Prospective Studies
MH  - Surveys and Questionnaires
MH  - *Travel
MH  - Yellow Fever/*prevention & control
MH  - Yellow Fever Vaccine/*adverse effects
MH  - Yellow fever virus
OTO - NOTNLM
OT  - Yellow fever
OT  - adverse event
OT  - elderly
OT  - questionnaire
OT  - traveller
OT  - vaccination
EDAT- 2016/03/30 06:00
MHDA- 2016/12/15 06:00
CRDT- 2016/03/30 06:00
PHST- 2016/02/22 00:00 [accepted]
PHST- 2016/03/30 06:00 [entrez]
PHST- 2016/03/30 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - taw012 [pii]
AID - 10.1093/jtm/taw012 [doi]
PST - epublish
SO  - J Travel Med. 2016 Mar 28;23(3):taw012. doi: 10.1093/jtm/taw012. Print 2016 Mar.