PMID- 27026494 OWN - NLM STAT- MEDLINE DCOM- 20170512 LR - 20170512 IS - 1879-2456 (Electronic) IS - 0956-053X (Linking) VI - 55 DP - 2016 Sep TI - Occurrence and treatment efficiency of pharmaceuticals in landfill leachates. PG - 257-64 LID - S0956-053X(16)30113-1 [pii] LID - 10.1016/j.wasman.2016.03.029 [doi] AB - Landfill leachates might contain pharmaceuticals due to the expired or unwanted drugs were disposed of at landfills. These pharmaceuticals might pose a threat to soil and groundwater. Therefore, this study investigated the distributions of pharmaceutical residues and toxicities among four typical municipal landfill leachates. Twenty six pharmaceuticals were investigated in this study and fifteen of them were found in all samples from four leachates. In addition, ampicillin and methylenedioxymethamphetamine (MDMA) were detected in urban landfills (A1 and A2) but were not in rural and suburb landfills (B and C). On the other hand, some compounds were much more abundant in suburb/rural landfill leachates than those in urban landfills including diclofenac, gemfibrozil and amphetamine. Landfill leachate treatment plants could not remove most of the pharmaceuticals effectively. Landfill leachates without proper treatments would have significant adverse health impacts on human and aquatic life. CI - Copyright (c) 2016 Elsevier Ltd. All rights reserved. FAU - Lu, Mu-Chen AU - Lu MC AD - Department of Environmental, Safety and Health Engineering, Hungkuang University, Taichung, Taiwan, ROC. FAU - Chen, Yao Yin AU - Chen YY AD - Department of Environmental, Safety and Health Engineering, Hungkuang University, Taichung, Taiwan, ROC. FAU - Chiou, Mei-Rung AU - Chiou MR AD - Department of Environmental, Safety and Health Engineering, Hungkuang University, Taichung, Taiwan, ROC. FAU - Chen, Men Yu AU - Chen MY AD - Department of Environmental, Safety and Health Engineering, Hungkuang University, Taichung, Taiwan, ROC. FAU - Fan, Huan-Jung AU - Fan HJ AD - Department of Environmental, Safety and Health Engineering, Hungkuang University, Taichung, Taiwan, ROC. Electronic address: fan@sunrise.hk.edu.tw. LA - eng PT - Journal Article DEP - 20160326 PL - United States TA - Waste Manag JT - Waste management (New York, N.Y.) JID - 9884362 RN - 0 (Pharmaceutical Preparations) RN - 0 (Water Pollutants, Chemical) SB - IM MH - Groundwater MH - Pharmaceutical Preparations/*analysis MH - Refuse Disposal MH - *Waste Disposal Facilities MH - Waste Disposal, Fluid/*methods MH - Water Pollutants, Chemical/*analysis OTO - NOTNLM OT - Landfill leachate OT - Pharmaceuticals OT - Toxicity OT - Treatment EDAT- 2016/03/31 06:00 MHDA- 2017/05/13 06:00 CRDT- 2016/03/31 06:00 PHST- 2015/11/04 00:00 [received] PHST- 2016/03/08 00:00 [revised] PHST- 2016/03/18 00:00 [accepted] PHST- 2016/03/31 06:00 [entrez] PHST- 2016/03/31 06:00 [pubmed] PHST- 2017/05/13 06:00 [medline] AID - S0956-053X(16)30113-1 [pii] AID - 10.1016/j.wasman.2016.03.029 [doi] PST - ppublish SO - Waste Manag. 2016 Sep;55:257-64. doi: 10.1016/j.wasman.2016.03.029. Epub 2016 Mar 26.