PMID- 27039392
OWN - NLM
STAT- MEDLINE
DCOM- 20160922
LR  - 20181202
IS  - 1534-6315 (Electronic)
IS  - 1529-7322 (Linking)
VI  - 16
IP  - 5
DP  - 2016 May
TI  - Pearls and Pitfalls in Diagnosing IgE-Mediated Food Allergy.
PG  - 34
LID - 10.1007/s11882-016-0611-z [doi]
AB  - The term "food allergy" is used by many patients and clinicians to describe a 
      range of symptoms that occur after ingestion of specific foods. However, not all 
      symptoms occurring after food exposure are due to an allergic, or immunologic, 
      response. It is important to properly evaluate and diagnose immunoglobulin E 
      (IgE)-mediated food allergy as this results in reproducible, immediate onset, 
      allergic reactions that can progress toward life-threatening anaphylaxis. Proper 
      diagnosis requires understanding of the common foods that cause these reactions 
      in addition to key historical elements such as symptoms, timing and duration of 
      reaction, and risk factors that may predispose to development of IgE-mediated 
      food allergy. Diagnostic testing for food-specific IgE can greatly aid the 
      diagnosis. However, false-positive test results are very common and can lead to 
      overinterpretation, misdiagnosis, and unnecessary dietary elimination. This 
      review discusses important aspects to consider during evaluation of a patient for 
      suspected IgE-mediated food allergy.
FAU - Stukus, David R
AU  - Stukus DR
AD  - Department of Pediatrics, Section of Allergy and Immunology, Nationwide 
      Children's Hospital and The Ohio State University College of Medicine, 700 
      Children's Drive, Columbus, Ohio, 43205, USA. 
      David.stukus@nationwidechildrens.org.
FAU - Mikhail, Irene
AU  - Mikhail I
AD  - Department of Pediatrics, Section of Allergy and Immunology, Nationwide 
      Children's Hospital and The Ohio State University College of Medicine, 700 
      Children's Drive, Columbus, Ohio, 43205, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Allergy Asthma Rep
JT  - Current allergy and asthma reports
JID - 101096440
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens/immunology
MH  - Anaphylaxis/immunology
MH  - Food Hypersensitivity/diagnosis/*immunology
MH  - Humans
MH  - Immunoglobulin E/*immunology
MH  - Physical Examination
MH  - Recurrence
OTO - NOTNLM
OT  - Anaphylaxis
OT  - Food allergy
OT  - Immunoglobulin E
OT  - Skin prick testing
OT  - Urticaria
EDAT- 2016/04/04 06:00
MHDA- 2016/09/23 06:00
CRDT- 2016/04/04 06:00
PHST- 2016/04/04 06:00 [entrez]
PHST- 2016/04/04 06:00 [pubmed]
PHST- 2016/09/23 06:00 [medline]
AID - 10.1007/s11882-016-0611-z [pii]
AID - 10.1007/s11882-016-0611-z [doi]
PST - ppublish
SO  - Curr Allergy Asthma Rep. 2016 May;16(5):34. doi: 10.1007/s11882-016-0611-z.