PMID- 27047693 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160406 LR - 20220321 IS - 2090-3057 (Print) IS - 2090-3065 (Electronic) IS - 2090-3057 (Linking) VI - 2016 DP - 2016 TI - Vancomycin and High Level Aminoglycoside Resistance in Enterococcus spp. in a Tertiary Health Care Centre: A Therapeutic Concern. PG - 8262561 LID - 10.1155/2016/8262561 [doi] LID - 8262561 AB - Aims. This study was aimed at knowing the prevalence of vancomycin and high level aminoglycoside resistance in enterococcal strains among clinical samples. Study Design. It was an investigational study. Place and Duration of Study. It was conducted on 100 Enterococcus isolates, in the Department of Microbiology, Pt. BDS PGIMS, Rohtak, over a period of six months from July to December 2014. Methodology. Clinical specimens including urine, pus, blood, semen, vaginal swab, and throat swab were processed and Enterococcus isolates were identified by standard protocols. Antibiotic sensitivity testing of enterococci was performed using Kirby-Bauer disc diffusion method. Results. High level gentamicin resistance (HLGR) was more common in urine samples (41.5%) followed by blood (36%) samples. High level streptomycin resistance (HLSR) was more common in pus samples (52.6%) followed by blood samples (36%). Resistance to vancomycin was maximum in blood isolates. Conclusion. Enterococci resistant to multiple antimicrobial agents have been recognized. Thus, it is crucial for laboratories to provide accurate antimicrobial resistance patterns for enterococci so that effective therapy and infection control measures can be initiated. FAU - Mittal, Seema AU - Mittal S AUID- ORCID: 0000-0002-4957-668X AD - BPS GMC (Women), Khanpur Kalan, Sonepat, Haryana, India. FAU - Singla, Pooja AU - Singla P AD - SHKMC, Mewat, Haryana, India. FAU - Deep, Antariksha AU - Deep A AD - PGIMS, Rohtak, Haryana, India. FAU - Bala, Kiran AU - Bala K AD - PGIMS, Rohtak, Haryana, India. FAU - Sikka, Rama AU - Sikka R AD - PGIMS, Rohtak, Haryana, India. FAU - Garg, Meenu AU - Garg M AD - PGIMS, Rohtak, Haryana, India. FAU - Chaudhary, Uma AU - Chaudhary U AD - PGIMS, Rohtak, Haryana, India. LA - eng PT - Journal Article DEP - 20160307 PL - Egypt TA - J Pathog JT - Journal of pathogens JID - 101571433 PMC - PMC4800106 EDAT- 2016/04/06 06:00 MHDA- 2016/04/06 06:01 PMCR- 2016/03/07 CRDT- 2016/04/06 06:00 PHST- 2015/10/11 00:00 [received] PHST- 2016/02/10 00:00 [revised] PHST- 2016/02/15 00:00 [accepted] PHST- 2016/04/06 06:00 [entrez] PHST- 2016/04/06 06:00 [pubmed] PHST- 2016/04/06 06:01 [medline] PHST- 2016/03/07 00:00 [pmc-release] AID - 10.1155/2016/8262561 [doi] PST - ppublish SO - J Pathog. 2016;2016:8262561. doi: 10.1155/2016/8262561. Epub 2016 Mar 7.