PMID- 27048345
OWN - NLM
STAT- MEDLINE
DCOM- 20170929
LR  - 20191210
IS  - 1526-4637 (Electronic)
IS  - 1526-2375 (Linking)
VI  - 18
IP  - 1
DP  - 2017 Jan 1
TI  - Validation of a New Placebo Interferential Current Method: A New Placebo Method 
      of Electrostimulation.
PG  - 86-94
LID - 10.1093/pm/pnw039 [doi]
AB  - OBJECTIVE: The present study aimed to investigate if a new placebo device for 
      interferential current (IFC) that delivers current during only the first 
      40 seconds of stimulation is effective at promoting adequate subject blinding. 
      METHODS: Seventy-five subjects were recruited and enrolled into three groups: 
      active IFC, inactive placebo, and new placebo. Pressure pain threshold (PPT), 
      cutaneous sensory threshold (CST), and pain intensity were measured before and 
      after the intervention. After the final assessment, the subjects and the 
      investigator who applied the current were asked about the type of stimulation 
      administered. RESULTS: None of the placebo forms studied resulted in significant 
      changes to PPT, CST, or pain intensity. The subjects stimulated with active IFC 
      at high intensities (> 17 mA) of stimulation showed higher PPT and CST and lower 
      pain intensity than subjects stimulated at low intensities ( p < 0.03). The new 
      placebo method blinded the investigator in 100% of cases of IFC and 60% of 
      subjects stimulated, whereas for inactive placebo, the investigator was blinded 
      at a rate of 0% and 34% of subjects. CONCLUSION: The new method of placebo IFC 
      was effective for blinding of research investigators and most of the active 
      IFC-treated subjects, promoting an appropriate placebo method.
CI  - (c) 2016 American Academy of Pain Medicine. All rights reserved. For permissions, 
      please e-mail: journals.permissions@oup.com
FAU - Mendonca Araujo, Fernanda
AU  - Mendonca Araujo F
AD  - Departamento de Fisioterapia, Universidade Federal de Sergipe, Aracaju, Se, 
      Brazil.
AD  - Programa de Pos-Graduacao em Ciencias Fisiologicas, Universidade Federal de 
      Sergipe, Aracaju, Se, Brazil.
FAU - Alves Menezes, Mayara
AU  - Alves Menezes M
AD  - Departamento de Fisioterapia, Universidade Federal de Sergipe, Aracaju, Se, 
      Brazil.
FAU - Martins de Araujo, Ariane
AU  - Martins de Araujo A
AD  - Departamento de Fisioterapia, Universidade Federal de Sergipe, Aracaju, Se, 
      Brazil.
FAU - Abner Dos Santos Sousa, Thiago
AU  - Abner Dos Santos Sousa T
AD  - Departamento de Fisioterapia, Universidade Federal de Sergipe, Aracaju, Se, 
      Brazil.
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Universidade Federal de Sergipe, 
      Aracaju, Se, Brazil.
FAU - Vasconcelos Lima, Lucas
AU  - Vasconcelos Lima L
AD  - Departamento de Fisioterapia, Universidade Federal de Sergipe, Aracaju, Se, 
      Brazil.
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Universidade Federal de Sergipe, 
      Aracaju, Se, Brazil.
FAU - Adan Nunes Carvalho, Elyson
AU  - Adan Nunes Carvalho E
AD  - Departamento de Engenharia Eletrica, Programa de Pos-Graduacao em Engenharia 
      Eletrica, Universidade Federal de Sergipe, Aracaju, Se, Brazil.
FAU - Melo DeSantana, Josimari
AU  - Melo DeSantana J
AD  - Departamento de Fisioterapia, Universidade Federal de Sergipe, Aracaju, Se, 
      Brazil.
AD  - Programa de Pos-Graduacao em Ciencias Fisiologicas, Universidade Federal de 
      Sergipe, Aracaju, Se, Brazil.
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Universidade Federal de Sergipe, 
      Aracaju, Se, Brazil.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Validation Study
PL  - England
TA  - Pain Med
JT  - Pain medicine (Malden, Mass.)
JID - 100894201
RN  - 0 (Placebos)
SB  - IM
MH  - Female
MH  - Humans
MH  - Male
MH  - *Pain Threshold
MH  - *Placebos
MH  - Transcutaneous Electric Nerve Stimulation/*methods
MH  - Young Adult
OTO - NOTNLM
OT  - Cutaneous Sensory Threshold
OT  - Electric Stimulation Therapy
OT  - Interferential Current
OT  - Pain Measurement
OT  - Placebo Effect
EDAT- 2016/04/07 06:00
MHDA- 2017/09/30 06:00
CRDT- 2016/04/07 06:00
PHST- 2016/04/07 06:00 [pubmed]
PHST- 2017/09/30 06:00 [medline]
PHST- 2016/04/07 06:00 [entrez]
AID - pnw039 [pii]
AID - 10.1093/pm/pnw039 [doi]
PST - ppublish
SO  - Pain Med. 2017 Jan 1;18(1):86-94. doi: 10.1093/pm/pnw039.