PMID- 27050285
OWN - NLM
STAT- MEDLINE
DCOM- 20170608
LR  - 20180404
IS  - 1520-5851 (Electronic)
IS  - 0013-936X (Linking)
VI  - 50
IP  - 9
DP  - 2016 May 3
TI  - Antioxidant Responses in Relation to Persistent Organic Pollutants and Metals in 
      a Low- and a High-Exposure Population of Seabirds.
PG  - 4817-25
LID - 10.1021/acs.est.6b00478 [doi]
AB  - Oxidative stress occurs when there is an imbalance between the production of 
      reactive oxygen species (ROS) and antioxidant defense. Exposure to pollutants may 
      increase ROS and affect antioxidant levels, and the resulting oxidative stress 
      may negatively affect both reproduction and survival. We measured concentrations 
      of 18 persistent organic pollutants (POPs) and 9 toxic elements in blood, as well 
      as total antioxidant capacity (TAC), total glutathione (tGSH), and carotenoids in 
      plasma of Baltic and Arctic female common eiders (Somateria mollissima) (N = 54) 
      at the end of their incubation-related fasting. The more polluted Baltic 
      population had higher TAC and tGSH concentrations compared to the Arctic 
      population. Carotenoid levels did not differ between populations. The effect of 
      mixtures of pollutants on the antioxidants was assessed, and the summed molar 
      blood concentrations of 14 POPs were positively related to TAC. There was no 
      significant relationship between the analyzed pollutants and tGSH concentrations. 
      The adaptive improvement of the antioxidant defense system in the Baltic 
      population may be a consequence of increased oxidative stress. However, both 
      increased oxidative stress and energy allocation toward antioxidant defense may 
      have adverse consequences for Baltic eiders at the incubation stage, when energy 
      resources reach an annual minimum due to incubation-related fasting.
FAU - Fenstad, Anette A
AU  - Fenstad AA
AD  - Department of Biology, Realfagbygget, Norwegian University of Science and 
      Technology (NTNU) , 7491 Trondheim, Norway.
FAU - Moody, A John
AU  - Moody AJ
AD  - School of Biological Sciences, Plymouth University , Drake Circus, Plymouth, 
      Devon PL4 8AA, U.K.
FAU - Ost, Markus
AU  - Ost M
AD  - Environmental and Marine Biology, Faculty of Science and Engineering, Abo Akademy 
      University , Artellerigatan 6, FI-20520 Turku, Finland.
AD  - Coastal Zone Research Team, Novia University of Applied Sciences (NOVIA) , 
      Raseborgsvagen 9, FI-10600 Ekenas, Finland.
FAU - Jaatinen, Kim
AU  - Jaatinen K
AD  - Coastal Zone Research Team, Novia University of Applied Sciences (NOVIA) , 
      Raseborgsvagen 9, FI-10600 Ekenas, Finland.
FAU - Bustnes, Jan O
AU  - Bustnes JO
AD  - Norwegian Institute for Nature Research (NINA), Framsenteret, Hjalmar Johansens 
      gate 14, 9296 Tromso, Norway.
FAU - Moe, Borge
AU  - Moe B
AD  - NINA, Hogskoleringen 9, 7034 Trondheim, Norway.
FAU - Hanssen, Sveinn A
AU  - Hanssen SA
AD  - Norwegian Institute for Nature Research (NINA), Framsenteret, Hjalmar Johansens 
      gate 14, 9296 Tromso, Norway.
FAU - Gabrielsen, Kristin M
AU  - Gabrielsen KM
AD  - Department of Biology, Realfagbygget, Norwegian University of Science and 
      Technology (NTNU) , 7491 Trondheim, Norway.
FAU - Herzke, Dorte
AU  - Herzke D
AD  - Norwegian Institute for Air Research (NILU), Framsenteret, Hjalmar Johansens gate 
      14, 9296 Tromso, Norway.
FAU - Lierhagen, Syverin
AU  - Lierhagen S
AD  - Department of Chemistry, Realfagbygget, Norwegian University of Science and 
      Technology (NTNU) , 7491 Trondheim, Norway.
FAU - Jenssen, Bjorn M
AU  - Jenssen BM
AD  - Department of Biology, Realfagbygget, Norwegian University of Science and 
      Technology (NTNU) , 7491 Trondheim, Norway.
FAU - Krokje, Ase
AU  - Krokje A
AD  - Department of Biology, Realfagbygget, Norwegian University of Science and 
      Technology (NTNU) , 7491 Trondheim, Norway.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160414
PL  - United States
TA  - Environ Sci Technol
JT  - Environmental science & technology
JID - 0213155
RN  - 0 (Antioxidants)
RN  - 0 (Metals)
RN  - 36-88-4 (Carotenoids)
RN  - GAN16C9B8O (Glutathione)
SB  - IM
MH  - Animals
MH  - Antioxidants/*pharmacology
MH  - Carotenoids/metabolism
MH  - Ducks
MH  - Glutathione/metabolism
MH  - Metals/*pharmacology
MH  - Oxidative Stress/drug effects
EDAT- 2016/04/07 06:00
MHDA- 2017/06/09 06:00
CRDT- 2016/04/07 06:00
PHST- 2016/04/07 06:00 [entrez]
PHST- 2016/04/07 06:00 [pubmed]
PHST- 2017/06/09 06:00 [medline]
AID - 10.1021/acs.est.6b00478 [doi]
PST - ppublish
SO  - Environ Sci Technol. 2016 May 3;50(9):4817-25. doi: 10.1021/acs.est.6b00478. Epub 
      2016 Apr 14.