PMID- 27051239 OWN - NLM STAT- MEDLINE DCOM- 20161220 LR - 20220409 IS - 1598-6357 (Electronic) IS - 1011-8934 (Print) IS - 1011-8934 (Linking) VI - 31 IP - 4 DP - 2016 Apr TI - Characteristics of Patients with Chronic Obstructive Pulmonary Disease at the First Visit to a Pulmonary Medical Center in Korea: The KOrea COpd Subgroup Study Team Cohort. PG - 553-60 LID - 10.3346/jkms.2016.31.4.553 [doi] AB - The Korea Chronic Obstructive Pulmonary Disorders Subgroup Study Team (Korea COPD Subgroup Study team, KOCOSS) is a multicenter observational study that includes 956 patients (mean age 69.9 +/- 7.8 years) who were enrolled from 45 tertiary and university-affiliated hospitals from December 2011 to October 2014. The initial evaluation for all patients included pulmonary function tests (PFT), 6-minute walk distance (6MWD), COPD Assessment Test (CAT), modified Medical Research Council (mMRC) dyspnea scale, and the COPD-specific version of St. George's Respiratory Questionnaire (SGRQ-C). Here, we report the comparison of baseline characteristics between patients with early- (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage I and II/groups A and B) and late-stage COPD (GOLD stage III and IV/groups C and D). Among all patients, the mean post-bronchodilator FEV1 was 55.8% +/- 16.7% of the predicted value, and most of the patients were in GOLD stage II (520, 56.9%) and group B (399, 42.0%). The number of exacerbations during one year prior to the first visit was significantly lower in patients with early COPD (0.4 vs. 0.9/0.1 vs. 1.2), as were the CAT score (13.9 vs. 18.3/13.5 vs. 18.1), mMRC (1.4 vs. 2.0/1.3 vs.1.9), and SGRQ-C total score (30.4 vs. 42.9/29.1 vs. 42.6) compared to late-stage COPD (all P < 0.001). Common comorbidities among all patients were hypertension (323, 37.7%), diabetes mellitus (139, 14.8%), and depression (207, 23.6%). The data from patients with early COPD will provide important information towards early detection, proper initial management, and design of future studies. FAU - Lee, Jung Yeon AU - Lee JY AUID- ORCID: 0000-0001-7011-620X AD - Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Konkuk University Chungju Hospital, Chungju, Korea . FAU - Chon, Gyu Rak AU - Chon GR AUID- ORCID: 0000-0003-4713-9213 AD - Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Konkuk University Chungju Hospital, Chungju, Korea . FAU - Rhee, Chin Kook AU - Rhee CK AUID- ORCID: 0000-0003-4533-7937 AD - Department of Internal Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea . FAU - Kim, Deog Kyeom AU - Kim DK AUID- ORCID: 0000-0001-9379-8098 AD - Department of Internal Medicine, Seoul Metropolitan Government, Seoul National University Boramae Medical Center, Seoul, Korea . FAU - Yoon, Hyoung Kyu AU - Yoon HK AUID- ORCID: 0000-0003-4783-2077 AD - Department of Internal Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea . FAU - Lee, Jin Hwa AU - Lee JH AUID- ORCID: 0000-0003-0843-9862 AD - Department of Internal Medicine, Medical Research Center, Ewha Womans University Medical Center, Seoul, Korea . FAU - Yoo, Kwang Ha AU - Yoo KH AUID- ORCID: 0000-0001-9969-2657 AD - Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea . FAU - Lee, Sang Haak AU - Lee SH AUID- ORCID: 0000-0001-6259-7656 AD - Department of Internal Medicine, The Catholic University of Korea, St. Paul's Hospital, Seoul, Korea . FAU - Lee, Sang Yeub AU - Lee SY AUID- ORCID: 0000-0001-7565-1076 AD - Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea . FAU - Kim, Tae-Eun AU - Kim TE AUID- ORCID: 0000-0001-7598-7602 AD - Department of Clinical Pharmacology, Konkuk University Medical Center, Seoul, Korea . FAU - Kim, Tae-Hyung AU - Kim TH AUID- ORCID: 0000-0002-3863-7854 AD - Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea . FAU - Park, Yong Bum AU - Park YB AUID- ORCID: 0000-0001-8810-6077 AD - Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Korea . FAU - Hwang, Yong Il AU - Hwang YI AUID- ORCID: 0000-0002-3502-5211 AD - Department of Internal Medicine, College of Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea . FAU - Kim, Young Sam AU - Kim YS AUID- ORCID: 0000-0001-9656-8482 AD - Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea . FAU - Jung, Ki Suck AU - Jung KS AUID- ORCID: 0000-0002-6878-6543 AD - Division of Pulmonary Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University Medical School, Anyang, Korea . LA - eng PT - Journal Article PT - Observational Study DEP - 20160310 PL - Korea (South) TA - J Korean Med Sci JT - Journal of Korean medical science JID - 8703518 SB - IM MH - Aged MH - Cohort Studies MH - Comorbidity MH - Depression/epidemiology MH - Diabetes Mellitus/epidemiology MH - Dyspnea/complications MH - Female MH - Forced Expiratory Volume MH - Hospitals, University MH - Humans MH - Hypertension/epidemiology MH - Lung/physiopathology MH - Male MH - Middle Aged MH - Pulmonary Disease, Chronic Obstructive/complications/*diagnosis/physiopathology MH - Quality of Life MH - Republic of Korea MH - Respiratory Function Tests MH - Severity of Illness Index MH - Societies, Medical MH - Surveys and Questionnaires MH - Tertiary Care Centers MH - Walk Test PMC - PMC4810338 OTO - NOTNLM OT - Pulmonary Disease, Chronic Obstructive OT - Questionnaires OT - Respiratory Function Tests COIS- DISCLOSURE: The authors have no potential conflicts of interest to disclose. EDAT- 2016/04/07 06:00 MHDA- 2016/12/21 06:00 PMCR- 2016/04/01 CRDT- 2016/04/07 06:00 PHST- 2015/07/29 00:00 [received] PHST- 2015/12/31 00:00 [accepted] PHST- 2016/04/07 06:00 [entrez] PHST- 2016/04/07 06:00 [pubmed] PHST- 2016/12/21 06:00 [medline] PHST- 2016/04/01 00:00 [pmc-release] AID - 10.3346/jkms.2016.31.4.553 [doi] PST - ppublish SO - J Korean Med Sci. 2016 Apr;31(4):553-60. doi: 10.3346/jkms.2016.31.4.553. Epub 2016 Mar 10.