PMID- 27051542 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160407 LR - 20200930 IS - 2090-6668 (Print) IS - 2090-6676 (Electronic) IS - 2090-6676 (Linking) VI - 2016 DP - 2016 TI - Septic Encephalopathy Characterized by Acute Encephalopathy with Biphasic Seizures and Late Reduced Diffusion and Early Nonconvulsive Status Epilepticus. PG - 7528238 LID - 10.1155/2016/7528238 [doi] LID - 7528238 AB - Infection, whether viral or bacterial, can result in various forms of brain dysfunction (encephalopathy). Septic encephalopathy (SE) is caused by an excessive immune reaction to infection, with clinical features including disturbed consciousness and seizures. Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is usually accompanied by viral infection in children and is characterized by biphasic seizures and impaired consciousness. The initial neurologic symptom of AESD is typically a febrile seizure that frequently lasts longer than 30 minutes. However, the possible forms this seizure takes are unclear. For example, it is unknown if nonconvulsive status epilepticus (NCSE) could be an early seizure symptomatic of AESD. In addition, thus far no cases of combined SE and AESD have been reported. Here, we describe the first reported case of SE with AESD that notably demonstrated NCSE as an early seizure. FAU - Yamaguchi, Hiroshi AU - Yamaguchi H AUID- ORCID: 0000-0002-0787-964X AD - Department of Emergency and Critical Care Medicine, Hyogo Prefectural Kobe Children's Hospital, 1-1-1 Takakuradai, Suma-Ku, Kobe, Hyogo 654-0081, Japan. FAU - Tanaka, Tsukasa AU - Tanaka T AD - Department of Neurology, Hyogo Prefectural Kobe Children's Hospital, 1-1-1 Takakuradai, Suma-Ku, Kobe, Hyogo 654-0081, Japan. FAU - Maruyama, Azusa AU - Maruyama A AD - Department of Neurology, Hyogo Prefectural Kobe Children's Hospital, 1-1-1 Takakuradai, Suma-Ku, Kobe, Hyogo 654-0081, Japan. FAU - Nagase, Hiroaki AU - Nagase H AD - Department of Neurology, Hyogo Prefectural Kobe Children's Hospital, 1-1-1 Takakuradai, Suma-Ku, Kobe, Hyogo 654-0081, Japan. LA - eng PT - Journal Article DEP - 20160309 PL - United States TA - Case Rep Neurol Med JT - Case reports in neurological medicine JID - 101576451 PMC - PMC4804049 EDAT- 2016/04/07 06:00 MHDA- 2016/04/07 06:01 PMCR- 2016/03/09 CRDT- 2016/04/07 06:00 PHST- 2015/11/16 00:00 [received] PHST- 2016/02/17 00:00 [accepted] PHST- 2016/04/07 06:00 [entrez] PHST- 2016/04/07 06:00 [pubmed] PHST- 2016/04/07 06:01 [medline] PHST- 2016/03/09 00:00 [pmc-release] AID - 10.1155/2016/7528238 [doi] PST - ppublish SO - Case Rep Neurol Med. 2016;2016:7528238. doi: 10.1155/2016/7528238. Epub 2016 Mar 9.