PMID- 27051604 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160407 LR - 20200930 IS - 2220-8372 (Print) IS - 2220-8372 (Electronic) IS - 2220-8372 (Linking) VI - 6 IP - 1 DP - 2016 Mar 21 TI - Collaborative activities and treatment outcomes in patients with HIV-associated tuberculosis in Viet Nam. PG - 8-14 LID - 10.5588/pha.16.0011 [doi] AB - SETTING: The National Tuberculosis (TB) Programme in Viet Nam and Ho Chi Minh City (HCMC). OBJECTIVES: To determine 1) at national level between 2011 and 2013, the relationship between human immunodeficiency virus (HIV) testing, uptake of TB-HIV interventions and adverse treatment outcomes among TB-HIV patients; and 2) in HCMC in 2013, patient characteristics associated with adverse outcomes. DESIGN: An ecological study reviewing aggregate nationwide data and a retrospective cohort review in HCMC. RESULTS: Nationwide, from 2011 to 2013, HIV testing increased in TB patients from 58% to 68% and antiretroviral therapy (ART) increased in TB-HIV patients from 54% to 63%. Adverse treatment outcomes in TB-HIV patients increased from 24% to 27%, largely due to transfer out (5-9% increase) and death. The Northern and Highland regions showed poor uptake of TB-HIV interventions. In HCMC, 303 (27%) of 1110 TB-HIV patients had adverse outcomes, with higher risks observed in those with previously treated TB, those diagnosed as HIV-positive before TB onset and those never placed on cotrimoxazole or ART. CONCLUSION: Despite improving HIV testing rates and TB-HIV interventions, adverse outcomes in TB-HIV patients remain at about 26%. Characteristics predicting higher risk of adverse outcomes must be addressed if Viet Nam wishes to end the TB epidemic by 2030. FAU - Huyen, T T T AU - Huyen TT AD - Viet Nam National Tuberculosis Control Programme/National Lung Hospital, Hanoi, Viet Nam. FAU - Nhung, N V AU - Nhung NV AD - Viet Nam National Tuberculosis Control Programme/National Lung Hospital, Hanoi, Viet Nam. FAU - Shewade, H D AU - Shewade HD AD - International Union Against Tuberculosis and Lung Disease (The Union) South-East Asia Regional Office, New Delhi, India. FAU - Hoa, N B AU - Hoa NB AD - Viet Nam National Tuberculosis Control Programme/National Lung Hospital, Hanoi, Viet Nam ; The Union, Paris, France. FAU - Harries, A D AU - Harries AD AD - The Union, Paris, France ; London School of Hygiene & Tropical Medicine, London, UK. LA - eng PT - Journal Article PL - France TA - Public Health Action JT - Public health action JID - 101624961 PMC - PMC4809731 OTO - NOTNLM OT - SORT IT OT - adverse treatment outcomes OT - antiretroviral therapy OT - cotrimoxazole preventive therapy OT - operational research EDAT- 2016/04/07 06:00 MHDA- 2016/04/07 06:01 PMCR- 2016/03/21 CRDT- 2016/04/07 06:00 PHST- 2016/01/19 00:00 [received] PHST- 2016/02/05 00:00 [accepted] PHST- 2016/04/07 06:00 [entrez] PHST- 2016/04/07 06:00 [pubmed] PHST- 2016/04/07 06:01 [medline] PHST- 2016/03/21 00:00 [pmc-release] AID - 10.5588/pha.16.0011 [doi] PST - ppublish SO - Public Health Action. 2016 Mar 21;6(1):8-14. doi: 10.5588/pha.16.0011.