PMID- 27053280
OWN - NLM
STAT- MEDLINE
DCOM- 20170807
LR  - 20220409
IS  - 1432-1998 (Electronic)
IS  - 0301-0449 (Linking)
VI  - 46
IP  - 9
DP  - 2016 Aug
TI  - How accurate is size-specific dose estimate in pediatric body CT examinations?
PG  - 1234-40
LID - 10.1007/s00247-016-3604-0 [doi]
AB  - BACKGROUND: Size-specific dose estimate is gaining increased acceptance as the 
      preferred index of CT dose in children. However it was developed based on 
      non-clinical data. OBJECTIVE: To compare the accuracy of size-specific dose 
      estimate (SSDE) based on geometric and body weight measures in pediatric chest 
      and abdomen CT scans, versus the more accurate [Formula: see text] (mean SSDE 
      based on water-equivalent diameter). MATERIALS AND METHODS: We retrospectively 
      identified 50 consecutive children (age <18 years) who underwent chest CT 
      examination and 50 children who underwent abdomen CT. We measured anteroposterior 
      diameter (DAP) and lateral diameter (DLAT) at the central slice (of scan length) 
      of each patient and calculated DAP+LAT (anteroposterior diameter plus lateral 
      diameter) and DED (effective diameter) for each patient. We calculated the 
      following in each child: (1) SSDEs based on DAP, DLAT, DAP+LAT, DED, and body 
      weight, and (2) SSDE based on software calculation of mean water-equivalent 
      diameter ([Formula: see text] adopted standard within our study). We used 
      intraclass correlation coefficient (ICC) and Bland-Altman analysis to compare 
      agreement between the SSDEs and [Formula: see text]. RESULTS: Gender and age 
      distribution were similar between chest and abdomen CT groups; mean body weight 
      was 37 kg for both groups, with ranges of 6-130 kg (chest) and 8-107 kg 
      (abdomen). SSDEs had very strong agreement (ICC>0.9) with [Formula: see text]. 
      SSDEs based on DLAT had 95% limits of agreement of up to 43% with [Formula: see 
      text]. SSDEs based on other parameters (body weight, DAP, DAP+LAT, DED) had 95% 
      limits of agreement of up to 25%. CONCLUSION: Differences between SSDEs 
      calculated using various indications of patient size (geometric indices and 
      patient weight) and the more accurate [Formula: see text] calculated using 
      proprietary software were generally small, with the possible exception for 
      lateral diameter, and provide acceptable dose estimates for body CT in children.
FAU - Karmazyn, Boaz
AU  - Karmazyn B
AD  - Department of Radiology, Riley Hospital for Children, 705 Riley Drive, Room 1053, 
      Indianapolis, IN, 46202, USA. bkarmazy@iupui.edu.
AD  - Department of Radiology and Imaging Sciences, Indiana University School of 
      Medicine, Indianapolis, IN, USA. bkarmazy@iupui.edu.
FAU - Ai, Huisi
AU  - Ai H
AD  - Department of Radiation Oncology, Indiana University School of Medicine, 
      Indianapolis, IN, USA.
FAU - Klahr, Paul
AU  - Klahr P
AD  - CT Clinical Science, Philips Healthcare, Highland Heights, OH, USA.
FAU - Ouyang, Fangqian
AU  - Ouyang F
AD  - Department of Biostatistics, Indiana University School of Medicine, Indianapolis, 
      IN, USA.
FAU - Jennings, S Gregory
AU  - Jennings SG
AD  - Department of Radiology and Imaging Sciences, Indiana University School of 
      Medicine, Indianapolis, IN, USA.
LA  - eng
PT  - Journal Article
DEP - 20160406
PL  - Germany
TA  - Pediatr Radiol
JT  - Pediatric radiology
JID - 0365332
SB  - IM
MH  - Adolescent
MH  - *Body Weight
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Radiation Dosage
MH  - Radiography, Abdominal
MH  - Radiography, Thoracic
MH  - Retrospective Studies
MH  - *Tomography, X-Ray Computed
OTO - NOTNLM
OT  - Abdomen
OT  - Chest
OT  - Children
OT  - Computed tomography dose index volume
OT  - Size-specific dose estimate
EDAT- 2016/04/08 06:00
MHDA- 2017/08/08 06:00
CRDT- 2016/04/08 06:00
PHST- 2015/10/24 00:00 [received]
PHST- 2016/03/01 00:00 [accepted]
PHST- 2016/02/01 00:00 [revised]
PHST- 2016/04/08 06:00 [entrez]
PHST- 2016/04/08 06:00 [pubmed]
PHST- 2017/08/08 06:00 [medline]
AID - 10.1007/s00247-016-3604-0 [pii]
AID - 10.1007/s00247-016-3604-0 [doi]
PST - ppublish
SO  - Pediatr Radiol. 2016 Aug;46(9):1234-40. doi: 10.1007/s00247-016-3604-0. Epub 2016 
      Apr 6.