PMID- 27055888
OWN - NLM
STAT- MEDLINE
DCOM- 20170322
LR  - 20181202
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 23
IP  - 14
DP  - 2016 Jul
TI  - Body burden of persistent organic pollutants on hypertension: a meta-analysis.
PG  - 14284-93
LID - 10.1007/s11356-016-6568-6 [doi]
AB  - Except the known risk factors for hypertension, several studies have suggested 
      that exposure to persistent organic pollutants (POPs), endocrine disrupting 
      chemicals, could be associated with an increased risk of hypertension. In this 
      study, we performed a meta-analysis to summarize the existing epidemiological 
      studies to investigate the association between POPs concentration and risk of 
      hypertension. Based on comprehensive literature search results (PubMed, EMBASE, 
      and KoreaMed), a meta-analysis of 11 articles was performed using a 
      random-effects model. While we observed no significant association between the 
      sum of non-dioxin-like PCBs and the risk of hypertension (OR = 1.00; 95 % CI 
      0.89, 1.12), the sum of dioxin-like PCBs was associated with a significantly 
      increased risk of hypertension (OR = 1.45; 95 % CI 1.00, 2.12). High p,p'-DDE 
      level was also significantly associated with the increased risk of hypertension. 
      When subgroup analyses were carried out for studies which analyzed POPs 
      concentrations using high-resolution gas chromatography/high-resolution mass 
      spectrometry, the overall pooled estimate ORs increased with decreased 
      heterogeneity, providing it as a possible heterogeneity source (OR = 1.36; 95 % 
      CI 1.21, 1.52; I (2) = 42.8 %; p = 0.045). This study suggested that the 
      concentration of certain POPs, especially dioxin-related compounds, was 
      associated with the risk of hypertension.
FAU - Park, Su Hyun
AU  - Park SH
AD  - Department of Preventive Medicine, School of Medicine, Ewha Womans University, 
      Seoul, Korea.
FAU - Lim, Jung-Eun
AU  - Lim JE
AD  - Institute for Health Promotion & Department of Epidemiology and Health Promotion, 
      Graduate School of Public Health, Yonsei University, Seoul, Korea.
AD  - Department of Public Health, Graduate School, Yonsei University, Seoul, Korea.
FAU - Park, Hyesook
AU  - Park H
AD  - Department of Preventive Medicine, School of Medicine, Ewha Womans University, 
      Seoul, Korea.
FAU - Jee, Sun Ha
AU  - Jee SH
AD  - Institute for Health Promotion & Department of Epidemiology and Health Promotion, 
      Graduate School of Public Health, Yonsei University, Seoul, Korea. 
      jsunha@yuhs.ac.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
DEP - 20160407
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Dioxins)
RN  - 0 (Endocrine Disruptors)
RN  - 0 (Environmental Pollutants)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Body Burden
MH  - Dioxins/*toxicity
MH  - Endocrine Disruptors
MH  - Environmental Pollutants/*toxicity
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Hypertension/*chemically induced/epidemiology
MH  - Polychlorinated Biphenyls/*toxicity
MH  - Risk Factors
OTO - NOTNLM
OT  - Blood pressure
OT  - Endocrine disruptors
OT  - Hypertension
OT  - Polychlorinated biphenyls
EDAT- 2016/04/09 06:00
MHDA- 2017/03/23 06:00
CRDT- 2016/04/09 06:00
PHST- 2016/01/27 00:00 [received]
PHST- 2016/03/27 00:00 [accepted]
PHST- 2016/04/09 06:00 [entrez]
PHST- 2016/04/09 06:00 [pubmed]
PHST- 2017/03/23 06:00 [medline]
AID - 10.1007/s11356-016-6568-6 [pii]
AID - 10.1007/s11356-016-6568-6 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2016 Jul;23(14):14284-93. doi: 
      10.1007/s11356-016-6568-6. Epub 2016 Apr 7.