PMID- 27057849
OWN - NLM
STAT- MEDLINE
DCOM- 20160825
LR  - 20210109
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 95
IP  - 14
DP  - 2016 Apr
TI  - 70% Alcohol Versus Dry Cord Care in the Umbilical Cord Care: A Case-Control Study 
      in Italy.
PG  - e3207
LID - 10.1097/MD.0000000000003207 [doi]
LID - e3207
AB  - Recently the use of antibacterial agents to clean and dry the stump of the 
      newborns' umbilical cord (UC) after birth has been abandoned by many neonatal 
      units in favor of dry cord care. Aim of this study was to compare the occurrence 
      of adverse events (AEs) and time to cord separation among newborns treated with 
      dry cord care versus 70% alcohol in an Italian Academic Hospital (AH).From 
      December 2014 to March 2015, 239 infants were born at the AH. The number of 
      eligible infants was 200 and they were equally assigned to either case group (dry 
      cord care) or control group (70% alcohol, standard procedure). Standard cord care 
      consisted in 1 application of 70% alcohol at birth followed by other 2 times a 
      day, while experimental dry cord care procedure was executed by the only 
      application of a sterile gauze around the base of the UC at the 1st day of life 
      and after the cord has been exposed to air off the diaper edge. The time to UC 
      separation and any AEs such as local and systemic infections, hemorrhage, and 
      granuloma formation were reported by mothers.We found a significant difference in 
      the mean cord separation time between the 2 groups (dry cord care: 10.1 days 
      [standard deviation, SD = 4.0] vs 70% alcohol: 12.0 days [SD = 4.2]; P < 0.001), 
      while no significant AEs resulted. Incidence rate of granuloma was 0.67 x 1000 
      days of life in dry cord care group.Dry cord care is an easy, straight-forward, 
      and safe method of handling the UC in healthy newborn infants born in a 
      high-income hospital setting.
FAU - Quattrin, Rosanna
AU  - Quattrin R
AD  - From the Azienda Ospedaliero-Universitaria "Santa Maria della Misericordia" (RQ, 
      ALDT, CP); School of Nursing, University of Udine (KI, LG); and Department of 
      Medical and Biological Sciences, University of Udine (SB), Udine, Italy.
FAU - Iacobucci, Kim
AU  - Iacobucci K
FAU - De Tina, Anna Lisa
AU  - De Tina AL
FAU - Gallina, Letizia
AU  - Gallina L
FAU - Pittini, Carla
AU  - Pittini C
FAU - Brusaferro, Silvio
AU  - Brusaferro S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 3K9958V90M (Ethanol)
SB  - IM
MH  - Case-Control Studies
MH  - Ethanol/*administration & dosage/adverse effects
MH  - Female
MH  - Humans
MH  - Infant Care/*methods
MH  - Infant, Newborn
MH  - Italy
MH  - Male
MH  - *Umbilical Cord
PMC - PMC4998765
COIS- The authors have no funding and conflicts of interest to disclose.
EDAT- 2016/04/09 06:00
MHDA- 2016/08/26 06:00
PMCR- 2016/04/08
CRDT- 2016/04/09 06:00
PHST- 2016/04/09 06:00 [entrez]
PHST- 2016/04/09 06:00 [pubmed]
PHST- 2016/08/26 06:00 [medline]
PHST- 2016/04/08 00:00 [pmc-release]
AID - 00005792-201604050-00025 [pii]
AID - 10.1097/MD.0000000000003207 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2016 Apr;95(14):e3207. doi: 10.1097/MD.0000000000003207.