PMID- 27060607
OWN - NLM
STAT- MEDLINE
DCOM- 20170629
LR  - 20181202
IS  - 1365-2036 (Electronic)
IS  - 0269-2813 (Linking)
VI  - 43
IP  - 11
DP  - 2016 Jun
TI  - Utilisation of surgical fundoplication for patients with gastro-oesophageal 
      reflux disease in the USA has declined rapidly between 2009 and 2013.
PG  - 1124-31
LID - 10.1111/apt.13611 [doi]
AB  - BACKGROUND: Surgical fundoplication has been considered to be one of the leading 
      therapeutic modalities for gastro-oesophageal reflux disease (GERD) during the 
      last several decades. AIM: To determine the trend of surgical fundoplication 
      utilisation in GERD patients during the last decade in the United States. 
      METHODS: Population-based study using a large nationwide database, the Explorys 
      database system, to identify patients diagnosed with GERD and those who underwent 
      surgical fundoplication. Using a quadratic regression model, we determined and 
      compared the trends of surgical fundoplication utilisation annually from 2004 to 
      2013. RESULTS: We identified 4 059 060 patients with the diagnosis of GERD, of 
      whom 2343 (0.05%) underwent surgical fundoplication between 2004 and 2013. There 
      was a significant decline in the number of surgical fundoplications performed 
      over the last 5 years from 0.062% in 2009 to 0.047% in 2013 (P < 0.05). Female 
      patients accounted for the majority of those who underwent fundoplication 
      (62.52%). Caucasian patients between the ages of 18 and 65 years were the most 
      likely group to undergo surgical fundoplication (66.28%). The number of 
      overweight patients undergoing surgical fundoplication has been significantly 
      increasing over the last decade (P < 0.05). Importantly, 80% of surgical patients 
      were treated with a proton pump inhibitor (PPI) post surgical fundoplication by 
      2013 (P < 0.001). CONCLUSIONS: Utilisation of surgical fundoplication in GERD 
      patients has been steadily declining over the past 5 years. The vast majority of 
      patients will resume PPI treatment after surgical fundoplication.
CI  - (c) 2016 John Wiley & Sons Ltd.
FAU - Khan, F
AU  - Khan F
AD  - The Esophageal and Swallowing Center, Division of Gastroenterology and 
      Hepatology, MetroHealth Medical Center, Case Western Reserve University, 
      Cleveland, OH, USA.
FAU - Maradey-Romero, C
AU  - Maradey-Romero C
AD  - The Esophageal and Swallowing Center, Division of Gastroenterology and 
      Hepatology, MetroHealth Medical Center, Case Western Reserve University, 
      Cleveland, OH, USA.
FAU - Ganocy, S
AU  - Ganocy S
AD  - Center Health Care Research and Policy, Case Western Reserve University at 
      MetroHealth Medical Center, Cleveland, OH, USA.
FAU - Frazier, R
AU  - Frazier R
AD  - The Esophageal and Swallowing Center, Division of Gastroenterology and 
      Hepatology, MetroHealth Medical Center, Case Western Reserve University, 
      Cleveland, OH, USA.
FAU - Fass, R
AU  - Fass R
AD  - The Esophageal and Swallowing Center, Division of Gastroenterology and 
      Hepatology, MetroHealth Medical Center, Case Western Reserve University, 
      Cleveland, OH, USA.
LA  - eng
PT  - Journal Article
DEP - 20160406
PL  - England
TA  - Aliment Pharmacol Ther
JT  - Alimentary pharmacology & therapeutics
JID - 8707234
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Databases, Factual
MH  - Female
MH  - Fundoplication/*methods
MH  - Gastroesophageal Reflux/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Overweight/epidemiology
MH  - Proton Pump Inhibitors/*therapeutic use
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2016/04/10 06:00
MHDA- 2017/07/01 06:00
CRDT- 2016/04/10 06:00
PHST- 2016/01/25 00:00 [received]
PHST- 2016/02/06 00:00 [revised]
PHST- 2016/03/03 00:00 [revised]
PHST- 2016/03/10 00:00 [revised]
PHST- 2016/03/11 00:00 [revised]
PHST- 2016/03/13 00:00 [accepted]
PHST- 2016/04/10 06:00 [entrez]
PHST- 2016/04/10 06:00 [pubmed]
PHST- 2017/07/01 06:00 [medline]
AID - 10.1111/apt.13611 [doi]
PST - ppublish
SO  - Aliment Pharmacol Ther. 2016 Jun;43(11):1124-31. doi: 10.1111/apt.13611. Epub 
      2016 Apr 6.